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Informing virtual clinical trials of hepatocellular carcinoma with spatial multi-omics analysis of a human neoadjuvant immunotherapy clinical trial.
Zhang S, Deshpande A, Verma BK, Wang H, Mi H, Yuan L, Ho WJ, Jaffee EM, Zhu Q, Anders RA, Yarchoan M, Kagohara LT, Fertig EJ, Popel AS. Zhang S, et al. Among authors: popel as. bioRxiv [Preprint]. 2023 Aug 15:2023.08.11.553000. doi: 10.1101/2023.08.11.553000. bioRxiv. 2023. PMID: 37645761 Free PMC article. Preprint.
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.
Zhang S, Yuan L, Danilova L, Mo G, Zhu Q, Deshpande A, Bell ATF, Elisseeff J, Popel AS, Anders RA, Jaffee EM, Yarchoan M, Fertig EJ, Kagohara LT. Zhang S, et al. Among authors: popel as. bioRxiv [Preprint]. 2023 Jan 12:2023.01.10.523481. doi: 10.1101/2023.01.10.523481. bioRxiv. 2023. PMID: 36712023 Free PMC article. Updated. Preprint.
Uncovering the spatial landscape of molecular interactions within the tumor microenvironment through latent spaces.
Deshpande A, Loth M, Sidiropoulos DN, Zhang S, Yuan L, Bell ATF, Zhu Q, Ho WJ, Santa-Maria C, Gilkes DM, Williams SR, Uytingco CR, Chew J, Hartnett A, Bent ZW, Favorov AV, Popel AS, Yarchoan M, Kiemen A, Wu PH, Fujikura K, Wirtz D, Wood LD, Zheng L, Jaffee EM, Anders RA, Danilova L, Stein-O'Brien G, Kagohara LT, Fertig EJ. Deshpande A, et al. Among authors: popel as. Cell Syst. 2023 Apr 19;14(4):285-301.e4. doi: 10.1016/j.cels.2023.03.004. Cell Syst. 2023. PMID: 37080163 Free PMC article.
Combining Multikinase Tyrosine Kinase Inhibitors Targeting the Vascular Endothelial Growth Factor and Cluster of Differentiation 47 Signaling Pathways Is Predicted to Increase the Efficacy of Antiangiogenic Combination Therapies.
Zhang Y, Popel AS, Bazzazi H. Zhang Y, et al. Among authors: popel as. ACS Pharmacol Transl Sci. 2023 Apr 18;6(5):710-726. doi: 10.1021/acsptsci.3c00008. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200806 Free PMC article.
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence.
Zhang S, Yuan L, Danilova L, Mo G, Zhu Q, Deshpande A, Bell ATF, Elisseeff J, Popel AS, Anders RA, Jaffee EM, Yarchoan M, Fertig EJ, Kagohara LT. Zhang S, et al. Among authors: popel as. Genome Med. 2023 Sep 18;15(1):72. doi: 10.1186/s13073-023-01218-y. Genome Med. 2023. PMID: 37723590 Free PMC article.
331 results