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Cellular models of alpha-synuclein toxicity and aggregation.
Delenclos M, Burgess JD, Lamprokostopoulou A, Outeiro TF, Vekrellis K, McLean PJ. Delenclos M, et al. Among authors: mclean pj. J Neurochem. 2019 Sep;150(5):566-576. doi: 10.1111/jnc.14806. Epub 2019 Jul 30. J Neurochem. 2019. PMID: 31265132 Free PMC article. Review.
APOE2 Exacerbates TDP-43 Related Toxicity in the Absence of Alzheimer Pathology.
Meneses AD, Koga S, Li Z, O'Leary J, Li F, Chen K, Murakami A, Qiao W, Kurti A, Heckman MG, White L, Xie M, Chen Y, Finch NA, Lim MJ, Delenclos M, DeTure MA, Linares C, Martin NB, Ikezu TC, van Blitterswijk MM, Wu LJ, McLean PJ, Rademakers R, Ross OA, Dickson DW, Bu G, Zhao N. Meneses AD, et al. Among authors: mclean pj. Ann Neurol. 2023 Apr;93(4):830-843. doi: 10.1002/ana.26580. Epub 2023 Jan 10. Ann Neurol. 2023. PMID: 36546684 Free PMC article.
A Mutant Methionyl-tRNA Synthetase-Based toolkit to assess induced-Mesenchymal Stromal Cell secretome in mixed-culture disease models.
Burgess JD, Amerna D, Norton ES, Parsons TM, Perkerson RB 3rd, Faroqi AH, Wszolek ZK, Cazares HG, Kanekiyo T, Delenclos M, McLean PJ. Burgess JD, et al. Among authors: mclean pj. Res Sq [Preprint]. 2023 May 3:rs.3.rs-2838195. doi: 10.21203/rs.3.rs-2838195/v1. Res Sq. 2023. PMID: 37205579 Free PMC article. Updated. Preprint.
Honokiol decreases alpha-synuclein mRNA levels and reveals novel targets for modulating alpha-synuclein expression.
Fagen SJ, Burgess JD, Lim MJ, Amerna D, Kaya ZB, Faroqi AH, Perisetla P, DeMeo NN, Stojkovska I, Quiriconi DJ, Mazzulli JR, Delenclos M, Boschen SL, McLean PJ. Fagen SJ, et al. Among authors: mclean pj. Front Aging Neurosci. 2023 Aug 10;15:1179086. doi: 10.3389/fnagi.2023.1179086. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37637959 Free PMC article.
Transcriptional mutagenesis of α-synuclein caused by DNA oxidation in Parkinson's disease pathogenesis.
Basu S, Song M, Adams L, Jeong I, Je G, Guhathakurta S, Jiang J, Boparai N, Dai W, Cardozo-Pelaez F, Tatulian SA, Han KY, Elliott J, Baum J, McLean PJ, Dickson DW, Kim YS. Basu S, et al. Among authors: mclean pj. Acta Neuropathol. 2023 Nov;146(5):685-705. doi: 10.1007/s00401-023-02632-7. Epub 2023 Sep 23. Acta Neuropathol. 2023. PMID: 37740734 Free PMC article.
Investigating the Pathogenic Interplay of Alpha-Synuclein, Tau, and Amyloid Beta in Lewy Body Dementia: Insights from Viral-Mediated Overexpression in Transgenic Mouse Models.
Lim MJ, Boschen SL, Kurti A, Castanedes Casey M, Phillips VR, Fryer JD, Dickson D, Jansen-West KR, Petrucelli L, Delenclos M, McLean PJ. Lim MJ, et al. Among authors: mclean pj. Biomedicines. 2023 Oct 22;11(10):2863. doi: 10.3390/biomedicines11102863. Biomedicines. 2023. PMID: 37893236 Free PMC article.
Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K. McKeith IG, et al. Neurology. 2017 Jul 4;89(1):88-100. doi: 10.1212/WNL.0000000000004058. Epub 2017 Jun 7. Neurology. 2017. PMID: 28592453 Free PMC article. Review.
106 results