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Sex-Dimorphic Analyses Identify Novel and Sex-Specific Genetic Associations in Inflammatory Bowel Disease.
Khrom M, Li D, Naito T, Lee HS, Botwin GJ, Potdar AA, Boucher G; NIDDK Inflammatory Bowel Disease Genetics Consortium; International Inflammatory Bowel Disease Genetics Consortium; Yang S, Mengesha E, Dube S, Song K, McGovern DPB, Haritunians T. Khrom M, et al. Among authors: yang s. Inflamm Bowel Dis. 2023 Oct 3;29(10):1622-1632. doi: 10.1093/ibd/izad089. Inflamm Bowel Dis. 2023. PMID: 37262302
Reduced expression of COVID-19 host receptor, ACE2 is associated with small bowel inflammation, more severe disease, and response to anti-TNF therapy in Crohn's disease.
Potdar AA, Dube S, Naito T, Botwin G, Haritunians T, Li D, Yang S, Bilsborough J, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Potdar AA, et al. Among authors: yang s. medRxiv [Preprint]. 2020 Apr 23:2020.04.19.20070995. doi: 10.1101/2020.04.19.20070995. medRxiv. 2020. PMID: 32511625 Free PMC article. Updated. Preprint.
Translocation of Viable Gut Microbiota to Mesenteric Adipose Drives Formation of Creeping Fat in Humans.
Ha CWY, Martin A, Sepich-Poore GD, Shi B, Wang Y, Gouin K, Humphrey G, Sanders K, Ratnayake Y, Chan KSL, Hendrick G, Caldera JR, Arias C, Moskowitz JE, Ho Sui SJ, Yang S, Underhill D, Brady MJ, Knott S, Kaihara K, Steinbaugh MJ, Li H, McGovern DPB, Knight R, Fleshner P, Devkota S. Ha CWY, et al. Among authors: yang s. Cell. 2020 Oct 29;183(3):666-683.e17. doi: 10.1016/j.cell.2020.09.009. Epub 2020 Sep 28. Cell. 2020. PMID: 32991841 Free PMC article.
Prevalence and Effect of Genetic Risk of Thromboembolic Disease in Inflammatory Bowel Disease.
Naito T, Botwin GJ, Haritunians T, Li D, Yang S, Khrom M, Braun J; NIDDK IBD Genetics Consortium; Abbou L, Mengesha E, Stevens C, Masamune A, Daly M, McGovern DPB. Naito T, et al. Among authors: yang s. Gastroenterology. 2021 Feb;160(3):771-780.e4. doi: 10.1053/j.gastro.2020.10.019. Epub 2020 Oct 21. Gastroenterology. 2021. PMID: 33098885 Free PMC article.
Altered Intestinal ACE2 Levels Are Associated With Inflammation, Severe Disease, and Response to Anti-Cytokine Therapy in Inflammatory Bowel Disease.
Potdar AA, Dube S, Naito T, Li K, Botwin G, Haritunians T, Li D, Casero D, Yang S, Bilsborough J, Perrigoue JG, Denson LA, Daly M, Targan SR, Fleshner P, Braun J, Kugathasan S, Stappenbeck TS, McGovern DPB. Potdar AA, et al. Among authors: yang s. Gastroenterology. 2021 Feb;160(3):809-822.e7. doi: 10.1053/j.gastro.2020.10.041. Epub 2020 Nov 5. Gastroenterology. 2021. PMID: 33160965 Free PMC article.
Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Akhlaghpour M, Haritunians T, More SK, Thomas LS, Stamps DT, Dube S, Li D, Yang S, Landers CJ, Mengesha E, Hamade H, Murali R, Potdar AA, Wolf AJ, Botwin GJ, Khrom M; International IBD Genetics Consortium; Ananthakrishnan AN, Faubion WA, Jabri B, Lira SA, Newberry RD, Sandler RS, Sartor RB, Xavier RJ, Brant SR, Cho JH, Duerr RH, Lazarev MG, Rioux JD, Schumm LP, Silverberg MS, Zaghiyan K, Fleshner P, Melmed GY, Vasiliauskas EA, Ha C, Rabizadeh S, Syal G, Bonthala NN, Ziring DA, Targan SR, Long MD, McGovern DPB, Michelsen KS. Akhlaghpour M, et al. Among authors: yang s. Gut. 2023 Nov;72(11):2068-2080. doi: 10.1136/gutjnl-2023-329689. Epub 2023 Apr 20. Gut. 2023. PMID: 37080587 Free article.
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