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OECD harmonised template 201: Structuring and reporting mechanistic information to foster the integration of new approach methodologies for hazard and risk assessment of chemicals.
Carnesecchi E, Langezaal I, Browne P, Batista-Leite S, Campia I, Coecke S, Dagallier B, Deceuninck P, Dorne JLC, Tarazona JV, Le Goff F, Leinala E, Morath S, Munn S, Richardson J, Paini A, Wittwehr C. Carnesecchi E, et al. Among authors: wittwehr c. Regul Toxicol Pharmacol. 2023 Aug;142:105426. doi: 10.1016/j.yrtph.2023.105426. Epub 2023 Jun 3. Regul Toxicol Pharmacol. 2023. PMID: 37277057 Review.
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.
Wittwehr C, Aladjov H, Ankley G, Byrne HJ, de Knecht J, Heinzle E, Klambauer G, Landesmann B, Luijten M, MacKay C, Maxwell G, Meek ME, Paini A, Perkins E, Sobanski T, Villeneuve D, Waters KM, Whelan M. Wittwehr C, et al. Toxicol Sci. 2017 Feb;155(2):326-336. doi: 10.1093/toxsci/kfw207. Epub 2016 Dec 19. Toxicol Sci. 2017. PMID: 27994170 Free PMC article.
COVID-19 through Adverse Outcome Pathways: Building networks to better understand the disease - 3rd CIAO AOP Design Workshop.
Clerbaux LA, Amigó N, Amorim MJ, Bal-Price A, Batista Leite S, Beronius A, Bezemer GFG, Bostroem AC, Carusi A, Coecke S, Concha R, Daskalopoulos EP, De Bernardi F, Edrosa E, Edwards SW, Filipovska J, Garcia-Reyero N, Gavins FNE, Halappanavar S, Hargreaves AJ, Hogberg HT, Huynh MT, Jacobson D, Josephs-Spaulding J, Kim YJ, Kong HJ, Krebs CE, Lam A, Landesmann B, Layton A, Lee YO, Macmillan DS, Mantovani A, Margiotta-Casaluci L, Martens M, Masereeuw R, Mayasich SA, Mei LM, Mortensen H, Munoz Pineiro A, Nymark P, Ohayon E, Ojasi J, Paini A, Parissis N, Parvatam S, Pistollato F, Sachana M, Sørli JB, Sullivan KM, Sund J, Tanabe S, Tsaioun K, Vinken M, Viviani L, Waspe J, Willett C, Wittwehr C. Clerbaux LA, et al. Among authors: wittwehr c. ALTEX. 2022;39(2):322–335. doi: 10.14573/altex.2112161. Epub 2022 Jan 3. ALTEX. 2022. PMID: 35032963 Free PMC article.
Towards a qAOP framework for predictive toxicology - Linking data to decisions.
Paini A, Campia I, Cronin MTD, Asturiol D, Ceriani L, Exner TE, Gao W, Gomes C, Kruisselbrink J, Martens M, Meek MEB, Pamies D, Pletz J, Scholz S, Schüttler A, Spînu N, Villeneuve DL, Wittwehr C, Worth A, Luijten M. Paini A, et al. Among authors: wittwehr c. Comput Toxicol. 2022 Feb;21:100195. doi: 10.1016/j.comtox.2021.100195. Comput Toxicol. 2022. PMID: 35211660 Free PMC article.
The Adverse Outcome Pathway Framework Applied to Neurological Symptoms of COVID-19.
Hogberg HT, Lam A, Ohayon E, Shahbaz MA, Clerbaux LA, Bal-Price A, Coecke S, Concha R, De Bernardi F, Edrosa E, Hargreaves AJ, Kanninen KM, Munoz A, Pistollato F, Saravanan S, Garcia-Reyero N, Wittwehr C, Sachana M. Hogberg HT, et al. Among authors: wittwehr c. Cells. 2022 Oct 28;11(21):3411. doi: 10.3390/cells11213411. Cells. 2022. PMID: 36359807 Free PMC article. Review.
Artificial Intelligence for chemical risk assessment.
Wittwehr C, Blomstedt P, Gosling JP, Peltola T, Raffael B, Richarz AN, Sienkiewicz M, Whaley P, Worth A, Whelan M. Wittwehr C, et al. Comput Toxicol. 2020 Feb;13:100114. doi: 10.1016/j.comtox.2019.100114. Comput Toxicol. 2020. PMID: 32140631 Free PMC article.
18 results