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Antibody-Associated Reversal of ATTR Amyloidosis-Related Cardiomyopathy.
Fontana M, Gilbertson J, Verona G, Riefolo M, Slamova I, Leone O, Rowczenio D, Botcher N, Ioannou A, Patel RK, Razvi Y, Martinez-Naharro A, Whelan CJ, Venneri L, Duhlin A, Canetti D, Ellmerich S, Moon JC, Kellman P, Al-Shawi R, McCoy L, Simons JP, Hawkins PN, Gillmore JD. Fontana M, et al. Among authors: verona g. N Engl J Med. 2023 Jun 8;388(23):2199-2201. doi: 10.1056/NEJMc2304584. N Engl J Med. 2023. PMID: 37285532 No abstract available.
Calcium Binds to Transthyretin with Low Affinity.
Cantarutti C, Mimmi MC, Verona G, Mandaliti W, Taylor GW, Mangione PP, Giorgetti S, Bellotti V, Corazza A. Cantarutti C, et al. Among authors: verona g. Biomolecules. 2022 Aug 2;12(8):1066. doi: 10.3390/biom12081066. Biomolecules. 2022. PMID: 36008960 Free PMC article.
A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis.
Marcoux J, Mangione PP, Porcari R, Degiacomi MT, Verona G, Taylor GW, Giorgetti S, Raimondi S, Sanglier-Cianférani S, Benesch JL, Cecconi C, Naqvi MM, Gillmore JD, Hawkins PN, Stoppini M, Robinson CV, Pepys MB, Bellotti V. Marcoux J, et al. Among authors: verona g. EMBO Mol Med. 2015 Oct;7(10):1337-49. doi: 10.15252/emmm.201505357. EMBO Mol Med. 2015. PMID: 26286619 Free PMC article.
A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.
Raimondi S, Porcari R, Mangione PP, Verona G, Marcoux J, Giorgetti S, Taylor GW, Ellmerich S, Ballico M, Zanini S, Pardon E, Al-Shawi R, Simons JP, Corazza A, Fogolari F, Leri M, Stefani M, Bucciantini M, Gillmore JD, Hawkins PN, Valli M, Stoppini M, Robinson CV, Steyaert J, Esposito G, Bellotti V. Raimondi S, et al. Among authors: verona g. Sci Rep. 2017 Apr 21;7:46711. doi: 10.1038/srep46711. Sci Rep. 2017. PMID: 28429761 Free PMC article.
Misidentification of transthyretin and immunoglobulin variants by proteomics due to methyl lysine formation in formalin-fixed paraffin-embedded amyloid tissue.
Canetti D, Rendell NB, Di Vagno L, Gilbertson JA, Rowczenio D, Rezk T, Gillmore JD, Hawkins PN, Verona G, Mangione PP, Giorgetti S, Mauri P, Motta S, De Palma A, Bellotti V, Taylor GW. Canetti D, et al. Among authors: verona g. Amyloid. 2017 Dec;24(4):233-241. doi: 10.1080/13506129.2017.1385452. Epub 2017 Oct 10. Amyloid. 2017. PMID: 29016222
Plasminogen activation triggers transthyretin amyloidogenesis in vitro.
Mangione PP, Verona G, Corazza A, Marcoux J, Canetti D, Giorgetti S, Raimondi S, Stoppini M, Esposito M, Relini A, Canale C, Valli M, Marchese L, Faravelli G, Obici L, Hawkins PN, Taylor GW, Gillmore JD, Pepys MB, Bellotti V. Mangione PP, et al. Among authors: verona g. J Biol Chem. 2018 Sep 14;293(37):14192-14199. doi: 10.1074/jbc.RA118.003990. Epub 2018 Jul 17. J Biol Chem. 2018. PMID: 30018138 Free PMC article.
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