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Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer.
Cancer Res. 2023 Aug 1;83(15):2471-2479. doi: 10.1158/0008-5472.CAN-22-2605.
Cancer Res. 2023.
PMID: 37289018
MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I.
Brägelmann J, Lorenz C, Borchmann S, Nishii K, Wegner J, Meder L, Ostendorp J, Ast DF, Heimsoeth A, Nakasuka T, Hirabae A, Okawa S, Dammert MA, Plenker D, Klein S, Lohneis P, Gu J, Godfrey LK, Forster J, Trajkovic-Arsic M, Zillinger T, Haarmann M, Quaas A, Lennartz S, Schmiel M, D'Rozario J, Thomas ES, Li H, Schmitt CA, George J, Thomas RK, von Karstedt S, Hartmann G, Büttner R, Ullrich RT, Siveke JT, Ohashi K, Schlee M, Sos ML.
Brägelmann J, et al. Among authors: ostendorp j.
Nat Commun. 2021 Sep 17;12(1):5505. doi: 10.1038/s41467-021-25728-8.
Nat Commun. 2021.
PMID: 34535668
Free PMC article.
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Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations.
Jutzi JS, Basu T, Pellmann M, Kaiser S, Steinemann D, Sanders MA, Hinai ASA, Zeilemaker A, Bojtine Kovacs S, Koellerer C, Ostendorp J, Aumann K, Wang W, Raffoux E, Cassinat B, Bullinger L, Schlegelberger B, Valk PJM, Pahl HL.
Jutzi JS, et al. Among authors: ostendorp j.
Blood. 2019 Apr 18;133(16):1766-1777. doi: 10.1182/blood-2018-09-875047. Epub 2019 Feb 12.
Blood. 2019.
PMID: 30755419
Free PMC article.
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Response of esophageal cancer cells to epigenetic inhibitors is mediated via altered thioredoxin activity.
Ahrens TD, Timme S, Ostendorp J, Bogatyreva L, Hoeppner J, Hopt UT, Hauschke D, Werner M, Lassmann S.
Ahrens TD, et al. Among authors: ostendorp j.
Lab Invest. 2016 Mar;96(3):307-16. doi: 10.1038/labinvest.2015.148. Epub 2015 Dec 21.
Lab Invest. 2016.
PMID: 26692290
Free article.
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Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine.
Ahrens TD, Timme S, Hoeppner J, Ostendorp J, Hembach S, Follo M, Hopt UT, Werner M, Busch H, Boerries M, Lassmann S.
Ahrens TD, et al. Among authors: ostendorp j.
Epigenetics. 2015;10(5):431-45. doi: 10.1080/15592294.2015.1039216.
Epigenetics. 2015.
PMID: 25923331
Free PMC article.
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