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Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injury.
Pryce KD, Serafini RA, Ramakrishnan A, Nicolais A, Giosan IM, Polizu C, Torres-Berrío A, Vuppala S, Kronman H, Ruiz A, Gaspari S, Peña CJ, Sakloth F, Mitsi V, van Duzer J, Mazitschek R, Jarpe M, Shen L, Nestler EJ, Zachariou V. Pryce KD, et al. Among authors: nestler ej. Nat Neurosci. 2023 Jul;26(7):1229-1244. doi: 10.1038/s41593-023-01350-3. Epub 2023 Jun 8. Nat Neurosci. 2023. PMID: 37291337
An essential role for DeltaFosB in the nucleus accumbens in morphine action.
Zachariou V, Bolanos CA, Selley DE, Theobald D, Cassidy MP, Kelz MB, Shaw-Lutchman T, Berton O, Sim-Selley LJ, Dileone RJ, Kumar A, Nestler EJ. Zachariou V, et al. Among authors: nestler ej. Nat Neurosci. 2006 Feb;9(2):205-11. doi: 10.1038/nn1636. Epub 2006 Jan 15. Nat Neurosci. 2006. PMID: 16415864
DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses.
Vialou V, Robison AJ, Laplant QC, Covington HE 3rd, Dietz DM, Ohnishi YN, Mouzon E, Rush AJ 3rd, Watts EL, Wallace DL, Iñiguez SD, Ohnishi YH, Steiner MA, Warren BL, Krishnan V, Bolaños CA, Neve RL, Ghose S, Berton O, Tamminga CA, Nestler EJ. Vialou V, et al. Among authors: nestler ej. Nat Neurosci. 2010 Jun;13(6):745-52. doi: 10.1038/nn.2551. Epub 2010 May 16. Nat Neurosci. 2010. PMID: 20473292 Free PMC article.
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens.
LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, Noonan MA, Ren Y, Eisch AJ, Bolaños CA, Kabbaj M, Xiao G, Neve RL, Hurd YL, Oosting RS, Fan G, Morrison JH, Nestler EJ. LaPlant Q, et al. Among authors: nestler ej. Nat Neurosci. 2010 Sep;13(9):1137-43. doi: 10.1038/nn.2619. Epub 2010 Aug 22. Nat Neurosci. 2010. PMID: 20729844 Free PMC article.
Transcriptional and epigenetic mechanisms of addiction.
Robison AJ, Nestler EJ. Robison AJ, et al. Among authors: nestler ej. Nat Rev Neurosci. 2011 Oct 12;12(11):623-37. doi: 10.1038/nrn3111. Nat Rev Neurosci. 2011. PMID: 21989194 Free PMC article. Review.
700 results