Hsu KL - Search Results

1

Predicting small molecule binding pockets on diacylglycerol kinases using chemoproteomics and AlphaFold.

Mendez R, Shaikh M, Lemke MC, Yuan K, Libby AH, Bai DL, Ross MM, Harris TE, Hsu KL. Mendez R, et al. Among authors: hsu kl. RSC Chem Biol. 2023 May 15;4(6):422-430. doi: 10.1039/d3cb00057e. eCollection 2023 Jun 7. RSC Chem Biol. 2023. PMID: 37292058 Free PMC article.

2

The Ligand Binding Landscape of Diacylglycerol Kinases.

Franks CE, Campbell ST, Purow BW, Harris TE, Hsu KL. Franks CE, et al. Among authors: hsu kl. Cell Chem Biol. 2017 Jul 20;24(7):870-880.e5. doi: 10.1016/j.chembiol.2017.06.007. Epub 2017 Jul 14. Cell Chem Biol. 2017. PMID: 28712745 Free PMC article.

3

Deconstructing Lipid Kinase Inhibitors by Chemical Proteomics.

McCloud RL, Franks CE, Campbell ST, Purow BW, Harris TE, Hsu KL. McCloud RL, et al. Among authors: hsu kl. Biochemistry. 2018 Jan 16;57(2):231-236. doi: 10.1021/acs.biochem.7b00962. Epub 2017 Nov 22. Biochemistry. 2018. PMID: 29155586 Free PMC article.

4

Global targeting of functional tyrosines using sulfur-triazole exchange chemistry.

Hahm HS, Toroitich EK, Borne AL, Brulet JW, Libby AH, Yuan K, Ware TB, McCloud RL, Ciancone AM, Hsu KL. Hahm HS, et al. Among authors: hsu kl. Nat Chem Biol. 2020 Feb;16(2):150-159. doi: 10.1038/s41589-019-0404-5. Epub 2019 Nov 25. Nat Chem Biol. 2020. PMID: 31768034 Free PMC article.

5

Automated Spatially Targeted Optical Microproteomics (autoSTOMP) to Determine Protein Complexity of Subcellular Structures.

Yin B, Mendez R, Zhao XY, Rakhit R, Hsu KL, Ewald SE. Yin B, et al. Among authors: hsu kl. Anal Chem. 2020 Jan 21;92(2):2005-2010. doi: 10.1021/acs.analchem.9b04396. Epub 2020 Jan 7. Anal Chem. 2020. PMID: 31869197 Free PMC article.

6

Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering.

Ware TB, Franks CE, Granade ME, Zhang M, Kim KB, Park KS, Gahlmann A, Harris TE, Hsu KL. Ware TB, et al. Among authors: hsu kl. Nat Chem Biol. 2020 Feb;16(2):170-178. doi: 10.1038/s41589-019-0445-9. Epub 2020 Jan 13. Nat Chem Biol. 2020. PMID: 31932721 Free PMC article.

7

Liganding Functional Tyrosine Sites on Proteins Using Sulfur-Triazole Exchange Chemistry.

Brulet JW, Borne AL, Yuan K, Libby AH, Hsu KL. Brulet JW, et al. Among authors: hsu kl. J Am Chem Soc. 2020 May 6;142(18):8270-8280. doi: 10.1021/jacs.0c00648. Epub 2020 Apr 24. J Am Chem Soc. 2020. PMID: 32329615 Free PMC article.

8

Lacritin proteoforms prevent tear film collapse and maintain epithelial homeostasis.

Georgiev GA, Gh MS, Romano J, Dias Teixeira KL, Struble C, Ryan DS, Sia RK, Kitt JP, Harris JM, Hsu KL, Libby A, Odrich MG, Suárez T, McKown RL, Laurie GW. Georgiev GA, et al. Among authors: hsu kl. J Biol Chem. 2021 Jan-Jun;296:100070. doi: 10.1074/jbc.RA120.015833. Epub 2020 Nov 21. J Biol Chem. 2021. PMID: 33187980 Free PMC article.

9

Discovery of a Cell-Active SuTEx Ligand of Prostaglandin Reductase 2.

Toroitich EK, Ciancone AM, Hahm HS, Brodowski SM, Libby AH, Hsu KL. Toroitich EK, et al. Among authors: hsu kl. Chembiochem. 2021 Jun 15;22(12):2134-2139. doi: 10.1002/cbic.202000879. Epub 2021 Apr 29. Chembiochem. 2021. PMID: 33861519 Free PMC article.

10

Monoacylglycerol Lipase Inhibition Using JZL184 Attenuates Paw Inflammation and Functional Deficits in a Mouse Model of Inflammatory Arthritis.

Nass SR, Steele FF, Ware TB, Libby AH, Hsu KL, Kinsey SG. Nass SR, et al. Among authors: hsu kl. Cannabis Cannabinoid Res. 2021 Jun;6(3):233-241. doi: 10.1089/can.2020.0177. Epub 2021 May 25. Cannabis Cannabinoid Res. 2021. PMID: 34042520 Free PMC article.

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