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Page 1
Longitudinal blood biomarker trajectories in preclinical Alzheimer's disease.
Yakoub Y, Ashton NJ, Strikwerda-Brown C, Montoliu-Gaya L, Karikari TK, Kac PR, Gonzalez-Ortiz F, Gallego-Rudolf J, Meyer PF, St-Onge F, Schöll M, Soucy JP, Breitner JCS, Zetterberg H, Blennow K, Poirier J, Villeneuve S; PREVENT-AD Research Group. Yakoub Y, et al. Among authors: soucy jp. Alzheimers Dement. 2023 Dec;19(12):5620-5631. doi: 10.1002/alz.13318. Epub 2023 Jun 9. Alzheimers Dement. 2023. PMID: 37294682
Association of Elevated Amyloid and Tau Positron Emission Tomography Signal With Near-Term Development of Alzheimer Disease Symptoms in Older Adults Without Cognitive Impairment.
Strikwerda-Brown C, Hobbs DA, Gonneaud J, St-Onge F, Binette AP, Ozlen H, Provost K, Soucy JP, Buckley RF, Benzinger TLS, Morris JC, Villemagne VL, Doré V, Sperling RA, Johnson KA, Rowe CC, Gordon BA, Poirier J, Breitner JCS, Villeneuve S; PREVENT-AD, HABS, and AIBL Research Groups. Strikwerda-Brown C, et al. Among authors: soucy jp. JAMA Neurol. 2022 Oct 1;79(10):975-985. doi: 10.1001/jamaneurol.2022.2379. JAMA Neurol. 2022. PMID: 35907254 Free PMC article.
Potential Utility of Plasma P-Tau and Neurofilament Light Chain as Surrogate Biomarkers for Preventive Clinical Trials.
Ferreira PCL, Ferrari-Souza JP, Tissot C, Bellaver B, Leffa DT, Lussier F, Povala G, Therriault J, Benedet AL, Ashton NJ, Cohen AD, Lopez OL, Tudorascu DL, Klunk WE, Soucy JP, Gauthier S, Villemagne V, Zetterberg H, Blennow K, Rosa-Neto P, Zimmer ER, Karikari TK, Pascoal TA; Alzheimer's Disease Neuroimaging Initiative. Ferreira PCL, et al. Among authors: soucy jp. Neurology. 2023 Jul 4;101(1):38-45. doi: 10.1212/WNL.0000000000207115. Epub 2023 Mar 6. Neurology. 2023. PMID: 36878697 Free PMC article.
Neuropsychiatric Symptoms and Microglial Activation in Patients with Alzheimer Disease.
Schaffer Aguzzoli C, Ferreira PCL, Povala G, Ferrari-Souza JP, Bellaver B, Soares Katz C, Zalzale H, Lussier FZ, Rohden F, Abbas S, Leffa DT, Scop Medeiros M, Therriault J, Benedet AL, Tissot C, Servaes S, Rahmouni N, Cassa Macedo A, Bezgin G, Kang MS, Stevenson J, Pallen V, Cohen A, Lopez OL, Tudorascu DL, Klunk WE, Villemagne VL, Soucy JP, Zimmer ER, Schilling LP, Karikari TK, Ashton NJ, Zetterberg H, Blennow K, Gauthier S, Valcour V, Miller BL, Rosa-Neto P, Pascoal TA. Schaffer Aguzzoli C, et al. Among authors: soucy jp. JAMA Netw Open. 2023 Nov 1;6(11):e2345175. doi: 10.1001/jamanetworkopen.2023.45175. JAMA Netw Open. 2023. PMID: 38010651 Free PMC article.
Structural white matter properties and cognitive resilience to tau pathology.
Qiu T, Liu ZQ, Rheault F, Legarreta JH, Valcourt Caron A, St-Onge F, Strikwerda-Brown C, Metz A, Dadar M, Soucy JP, Pichet Binette A, Spreng RN, Descoteaux M, Villeneuve S; PREVENT‐AD Research Group. Qiu T, et al. Among authors: soucy jp. Alzheimers Dement. 2024 May;20(5):3364-3377. doi: 10.1002/alz.13776. Epub 2024 Apr 1. Alzheimers Dement. 2024. PMID: 38561254 Free PMC article.
Distinct spatial contributions of amyloid pathology and cerebral small vessel disease to hippocampal morphology.
Xhima K, Ottoy J, Gibson E, Zukotynski K, Scott C, Feliciano GJ, Adamo S, Kuo PH, Borrie MJ, Chertkow H, Frayne R, Laforce R Jr, Noseworthy MD, Prato FS, Sahlas DJ, Smith EE, Sossi V, Thiel A, Soucy JP, Tardif JC, Goubran M, Black SE, Ramirez J; Medical Imaging Trials Network of Canada (MITNEC). Xhima K, et al. Among authors: soucy jp. Alzheimers Dement. 2024 May;20(5):3687-3695. doi: 10.1002/alz.13791. Epub 2024 Apr 4. Alzheimers Dement. 2024. PMID: 38574400 Free PMC article.
The Association of Age-Related and Off-Target Retention with Longitudinal Quantification of [18F]MK6240 Tau PET in Target Regions.
Tissot C, Servaes S, Lussier FZ, Ferrari-Souza JP, Therriault J, Ferreira PCL, Bezgin G, Bellaver B, Leffa DT, Mathotaarachchi SS, Chamoun M, Stevenson J, Rahmouni N, Kang MS, Pallen V, Margherita-Poltronetti N, Wang YT, Fernandez-Arias J, Benedet AL, Zimmer ER, Soucy JP, Tudorascu DL, Cohen AD, Sharp M, Gauthier S, Massarweh G, Lopresti B, Klunk WE, Baker SL, Villemagne VL, Rosa-Neto P, Pascoal TA. Tissot C, et al. Among authors: soucy jp. J Nucl Med. 2023 Mar;64(3):452-459. doi: 10.2967/jnumed.122.264434. Epub 2022 Nov 17. J Nucl Med. 2023. PMID: 36396455 Free PMC article.
Intra-individual comparison of 18F-sodium fluoride PET-CT and 99mTc bone scintigraphy with SPECT in patients with prostate cancer or breast cancer at high risk for skeletal metastases (MITNEC-A1): a multicentre, phase 3 trial.
Bénard F, Harsini S, Wilson D, Zukotynski K, Abikhzer G, Turcotte E, Cossette M, Metser U, Romsa J, Martin M, Mar C, Saad F, Soucy JP, Eigl BJ, Black P, Krauze A, Burrell S, Nichol A, Tardif JC. Bénard F, et al. Among authors: soucy jp. Lancet Oncol. 2022 Dec;23(12):1499-1507. doi: 10.1016/S1470-2045(22)00642-8. Epub 2022 Nov 4. Lancet Oncol. 2022. PMID: 36343655 Clinical Trial.
Parkinson's disease CA2-CA3 hippocampal atrophy is accompanied by increased cholinergic innervation in patients with normal cognition but not in patients with mild cognitive impairment.
Legault-Denis C, Aumont É, Onuska KM, Schmitz TW, Bussy A, Chakravarty M, Soucy JP, Bédard MA. Legault-Denis C, et al. Among authors: soucy jp. Brain Imaging Behav. 2024 Mar 13. doi: 10.1007/s11682-024-00872-z. Online ahead of print. Brain Imaging Behav. 2024. PMID: 38478257
Plasma p-tau217 predicts cognitive impairments up to ten years before onset in normal older adults.
Yakoub Y, Gonzalez-Ortiz F, Ashton NJ, Déry C, Strikwerda-Brown C, St-Onge F, Ourry V, Schöll M, Geddes MR, Ducharme S, Montembeault M, Rosa-Neto P, Soucy JP, Breitner JCS, Zetterberg H, Blennow K, Poirier J, Villeneuve S; PREVENT-AD Research Group. Yakoub Y, et al. Among authors: soucy jp. medRxiv [Preprint]. 2024 May 9:2024.05.09.24307120. doi: 10.1101/2024.05.09.24307120. medRxiv. 2024. PMID: 38766113 Free PMC article. Preprint.
207 results