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An astrocyte BMAL1-BAG3 axis protects against alpha-synuclein and tau pathology.
Sheehan PW, Nadarajah CJ, Kanan MF, Patterson JN, Novotny B, Lawrence JH, King MW, Brase L, Inman CE, Yuede CM, Lee J, Patel TK, Harari O, Benitez BA, Davis AA, Musiek ES. Sheehan PW, et al. Neuron. 2023 Aug 2;111(15):2383-2398.e7. doi: 10.1016/j.neuron.2023.05.006. Epub 2023 Jun 13. Neuron. 2023. PMID: 37315555
Cell-Autonomous Regulation of Astrocyte Activation by the Circadian Clock Protein BMAL1.
Lananna BV, Nadarajah CJ, Izumo M, Cedeño MR, Xiong DD, Dimitry J, Tso CF, McKee CA, Griffin P, Sheehan PW, Haspel JA, Barres BA, Liddelow SA, Takahashi JS, Karatsoreos IN, Musiek ES. Lananna BV, et al. Among authors: sheehan pw. Cell Rep. 2018 Oct 2;25(1):1-9.e5. doi: 10.1016/j.celrep.2018.09.015. Cell Rep. 2018. PMID: 30282019 Free PMC article.
Circadian clock protein Rev-erbα regulates neuroinflammation.
Griffin P, Dimitry JM, Sheehan PW, Lananna BV, Guo C, Robinette ML, Hayes ME, Cedeño MR, Nadarajah CJ, Ezerskiy LA, Colonna M, Zhang J, Bauer AQ, Burris TP, Musiek ES. Griffin P, et al. Among authors: sheehan pw. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):5102-5107. doi: 10.1073/pnas.1812405116. Epub 2019 Feb 21. Proc Natl Acad Sci U S A. 2019. PMID: 30792350 Free PMC article.
Dural lymphatics regulate clearance of extracellular tau from the CNS.
Patel TK, Habimana-Griffin L, Gao X, Xu B, Achilefu S, Alitalo K, McKee CA, Sheehan PW, Musiek ES, Xiong C, Coble D, Holtzman DM. Patel TK, et al. Among authors: sheehan pw. Mol Neurodegener. 2019 Feb 27;14(1):11. doi: 10.1186/s13024-019-0312-x. Mol Neurodegener. 2019. PMID: 30813965 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 34971131
85 results