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231 results

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Page 1
Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy.
Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, Moeser M, Sondgeroth AL, Whitehill GD, Singh V, Dashti A, Smith DM, Eron JJ, Bar KJ, Chahroudi A, Joseph SB, Archin NM, Margolis DM, Jiang G. Tang Y, et al. Among authors: allard b. J Clin Invest. 2023 Jun 15;133(12):e167417. doi: 10.1172/JCI167417. J Clin Invest. 2023. PMID: 37317962 Free PMC article.
Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency.
Archin NM, Kirchherr JL, Sung JA, Clutton G, Sholtis K, Xu Y, Allard B, Stuelke E, Kashuba AD, Kuruc JD, Eron J, Gay CL, Goonetilleke N, Margolis DM. Archin NM, et al. Among authors: allard b. J Clin Invest. 2017 Aug 1;127(8):3126-3135. doi: 10.1172/JCI92684. Epub 2017 Jul 17. J Clin Invest. 2017. PMID: 28714868 Free PMC article.
Impact of Biological Sex on Immune Activation and Frequency of the Latent HIV Reservoir During Suppressive Antiretroviral Therapy.
Falcinelli SD, Shook-Sa BE, Dewey MG, Sridhar S, Read J, Kirchherr J, James KS, Allard B, Ghofrani S, Stuelke E, Baker C, Roan NR, Eron JJ, Kuruc JD, Ramirez C, Gay C, Mollan KR, Margolis DM, Adimora AA, Archin NM. Falcinelli SD, et al. Among authors: allard b. J Infect Dis. 2020 Nov 9;222(11):1843-1852. doi: 10.1093/infdis/jiaa298. J Infect Dis. 2020. PMID: 32496542 Free PMC article.
Longitudinal Dynamics of Intact HIV Proviral DNA and Outgrowth Virus Frequencies in a Cohort of Individuals Receiving Antiretroviral Therapy.
Falcinelli SD, Kilpatrick KW, Read J, Murtagh R, Allard B, Ghofrani S, Kirchherr J, James KS, Stuelke E, Baker C, Kuruc JD, Eron JJ, Hudgens MG, Gay CL, Margolis DM, Archin NM. Falcinelli SD, et al. Among authors: allard b. J Infect Dis. 2021 Jul 2;224(1):92-100. doi: 10.1093/infdis/jiaa718. J Infect Dis. 2021. PMID: 33216132 Free PMC article.
Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat.
Gay CL, James KS, Tuyishime M, Falcinelli SD, Joseph SB, Moeser MJ, Allard B, Kirchherr JL, Clohosey M, Raines SLM, Montefiori DC, Shen X, Gorelick RJ, Gama L, McDermott AB, Koup RA, Mascola JR, Floris-Moore M, Kuruc JD, Ferrari G, Eron JJ, Archin NM, Margolis DM. Gay CL, et al. Among authors: allard b. J Infect Dis. 2022 Mar 2;225(5):856-861. doi: 10.1093/infdis/jiab487. J Infect Dis. 2022. PMID: 34562096 Free PMC article.
Combined noncanonical NF-κB agonism and targeted BET bromodomain inhibition reverse HIV latency ex vivo.
Falcinelli SD, Peterson JJ, Turner AW, Irlbeck D, Read J, Raines SL, James KS, Sutton C, Sanchez A, Emery A, Sampey G, Ferris R, Allard B, Ghofrani S, Kirchherr JL, Baker C, Kuruc JD, Gay CL, James LI, Wu G, Zuck P, Rioja I, Furze RC, Prinjha RK, Howell BJ, Swanstrom R, Browne EP, Strahl BD, Dunham RM, Archin NM, Margolis DM. Falcinelli SD, et al. Among authors: allard b. J Clin Invest. 2022 Apr 15;132(8):e157281. doi: 10.1172/JCI157281. J Clin Invest. 2022. PMID: 35426377 Free PMC article.
Depletion of HIV reservoir by activation of ISR signaling in resting CD4+T cells.
Li D, Wong LM, Tang Y, Allard B, James KS, Thompson GR, Dandekar S, Browne EP, Li Q, Simon JM, Archin NM, Margolis DM, Jiang G. Li D, et al. Among authors: allard b. iScience. 2022 Dec 7;26(1):105743. doi: 10.1016/j.isci.2022.105743. eCollection 2023 Jan 20. iScience. 2022. PMID: 36590168 Free PMC article.
Assessing the impact of AGS-004, a dendritic cell-based immunotherapy, and vorinostat on persistent HIV-1 Infection.
Gay CL, Kuruc JD, Falcinelli SD, Warren JA, Reifeis SA, Kirchherr JL, James KS, Dewey MG, Helms A, Allard B, Stuelke E, Gamble A, Plachco A, Gorelick RJ, Eron JJ, Hudgens M, Garrido C, Goonetilleke N, DeBenedette MA, Tcherepanova IY, Nicolette CA, Archin NM, Margolis DM. Gay CL, et al. Among authors: allard b. Sci Rep. 2020 Mar 20;10(1):5134. doi: 10.1038/s41598-020-61878-3. Sci Rep. 2020. PMID: 32198428 Free PMC article.
231 results