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Neutralizing RGMa with Elezanumab Promotes Cerebroprotection and Recovery in Rabbit Middle Cerebral Artery Occlusion.
Jacobson PB, Mothe A, Levy A, Krakovsky M, Hooker BA, Zhang X, Mollon J, Mordashova Y, Droescher M, Weiss S, Barghorn S, Dreher I, Awwad K, Nimmrich V, Huang L, Fung E, Buck WR, Pfleeger K, Ziemann A, Smith E, Fox GB, Tator CH, Gold M. Jacobson PB, et al. Among authors: pfleeger k. Transl Stroke Res. 2023 Jun 16. doi: 10.1007/s12975-023-01164-2. Online ahead of print. Transl Stroke Res. 2023. PMID: 37326791
Elezanumab, a human anti-RGMa monoclonal antibody, promotes neuroprotection, neuroplasticity, and neurorecovery following a thoracic hemicompression spinal cord injury in non-human primates.
Jacobson PB, Goody R, Lawrence M, Mueller BK, Zhang X, Hooker BA, Pfleeger K, Ziemann A, Locke C, Barraud Q, Droescher M, Bernhard J, Popp A, Boeser P, Huang L, Mollon J, Mordashova Y, Cui YF, Savaryn JP, Grinnell C, Dreher I, Gold M, Courtine G, Mothe A, Tator CH, Guest JD. Jacobson PB, et al. Among authors: pfleeger k. Neurobiol Dis. 2021 Jul;155:105385. doi: 10.1016/j.nbd.2021.105385. Epub 2021 May 12. Neurobiol Dis. 2021. PMID: 33991647 Free article.