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Neuroprotection after cardiac arrest with 2-iminobiotin: a single center phase IIa study on safety, tolerability, and pharmacokinetics.
Front Neurol. 2023 Jun 2;14:1136046. doi: 10.3389/fneur.2023.1136046. eCollection 2023.
Front Neurol. 2023.
PMID: 37332991
Free PMC article.
Pharmacokinetics and short-term safety of the selective NOS inhibitor 2-iminobiotin in asphyxiated neonates treated with therapeutic hypothermia.
Favié LMA, Peeters-Scholte CMPCD, Bakker A, Tjabbes H, Egberts TCG, van Bel F, Rademaker CMA, Vis P, Groenendaal F.
Favié LMA, et al. Among authors: tjabbes h.
Pediatr Res. 2020 Mar;87(4):689-696. doi: 10.1038/s41390-019-0587-1. Epub 2019 Oct 2.
Pediatr Res. 2020.
PMID: 31578035
Clinical Trial.
Item in Clipboard
A Phase IIa Clinical Trial of 2-Iminobiotin for the Treatment of Birth Asphyxia in DR Congo, a Low-Income Country.
Biselele T, Bambi J, Betukumesu DM, Ndiyo Y, Tabu G, Kapinga J, Bola V, Makaya P, Tjabbes H, Vis P, Peeters-Scholte C.
Biselele T, et al. Among authors: tjabbes h.
Paediatr Drugs. 2020 Feb;22(1):95-104. doi: 10.1007/s40272-019-00373-3.
Paediatr Drugs. 2020.
PMID: 31960360
Clinical Trial.
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Observational study shows that it is feasible to provide neuroprotective treatment for neonatal encephalopathy in low-income countries.
Biselele T, Bambi J, Naulaers G, Tabu G, Kapinga J, Bola V, Makaya P, Tjabbes H, Tady B, Peeters-Scholte C.
Biselele T, et al. Among authors: tjabbes h.
Acta Paediatr. 2018 Aug;107(8):1345-1349. doi: 10.1111/apa.14263. Epub 2018 Mar 1.
Acta Paediatr. 2018.
PMID: 29424938
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Translation from animal to clinical studies, choosing the optimal moment.
Favié LMA, Peeters-Scholte CMPCD, Bakker A, Tjabbes H, Egberts TCG, van Bel F, Rademaker CMA, Vis P, Groenendaal F.
Favié LMA, et al. Among authors: tjabbes h.
Pediatr Res. 2020 Dec;88(6):836-837. doi: 10.1038/s41390-020-0820-y. Epub 2020 Feb 19.
Pediatr Res. 2020.
PMID: 32074625
No abstract available.
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Donor screening: an overview of current regulation and practices in Europe.
Tjabbes H.
Tjabbes H.
Transplant Proc. 1996 Oct;28(5):2950-2.
Transplant Proc. 1996.
PMID: 8908136
Review.
No abstract available.
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