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Efficient production of bispecific antibody by FAST-IgTM and its application to NXT007 for the treatment of hemophilia A.
Koga H, Yamano T, Betancur J, Nagatomo S, Ikeda Y, Yamaguchi K, Nabuchi Y, Sato K, Teranishi-Ikawa Y, Sato M, Hirayama H, Hayasaka A, Torizawa T, Haraya K, Sampei Z, Shiraiwa H, Kitazawa T, Igawa T, Kuramochi T. Koga H, et al. Among authors: kuramochi t. MAbs. 2023 Jan-Dec;15(1):2222441. doi: 10.1080/19420862.2023.2222441. MAbs. 2023. PMID: 37339067 Free PMC article.
Engineering the variable region of therapeutic IgG antibodies.
Igawa T, Tsunoda H, Kuramochi T, Sampei Z, Ishii S, Hattori K. Igawa T, et al. Among authors: kuramochi t. MAbs. 2011 May-Jun;3(3):243-52. doi: 10.4161/mabs.3.3.15234. Epub 2011 May 1. MAbs. 2011. PMID: 21406966 Free PMC article. Review.
Fc Engineering to Improve the Function of Therapeutic Antibodies.
Mimoto F, Kuramochi T, Katada H, Igawa T, Hattori K. Mimoto F, et al. Among authors: kuramochi t. Curr Pharm Biotechnol. 2016;17(15):1298-1314. doi: 10.2174/1389201017666160824161854. Curr Pharm Biotechnol. 2016. PMID: 27552846
Engineering a bispecific antibody with a common light chain: Identification and optimization of an anti-CD3 epsilon and anti-GPC3 bispecific antibody, ERY974.
Shiraiwa H, Narita A, Kamata-Sakurai M, Ishiguro T, Sano Y, Hironiwa N, Tsushima T, Segawa H, Tsunenari T, Ikeda Y, Kayukawa Y, Noguchi M, Wakabayashi T, Sakamoto A, Konishi H, Kuramochi T, Endo M, Hattori K, Nezu J, Igawa T. Shiraiwa H, et al. Among authors: kuramochi t. Methods. 2019 Feb 1;154:10-20. doi: 10.1016/j.ymeth.2018.10.005. Epub 2018 Oct 13. Methods. 2019. PMID: 30326272
Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody.
Sampei Z, Haraya K, Tachibana T, Fukuzawa T, Shida-Kawazoe M, Gan SW, Shimizu Y, Ruike Y, Feng S, Kuramochi T, Muraoka M, Kitazawa T, Kawabe Y, Igawa T, Hattori K, Nezu J. Sampei Z, et al. Among authors: kuramochi t. PLoS One. 2018 Dec 28;13(12):e0209509. doi: 10.1371/journal.pone.0209509. eCollection 2018. PLoS One. 2018. PMID: 30592762 Free PMC article.
160 results