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Page 1
Prevalence of Deleterious Variants in MC3R in Patients With Constitutional Delay of Growth and Puberty.
Duckett K, Williamson A, Kincaid JWR, Rainbow K, Corbin LJ, Martin HC, Eberhardt RY, Huang QQ, Hurles ME, He W, Brauner R, Delaney A, Dunkel L, Grinspon RP, Hall JE, Hirschhorn JN, Howard SR, Latronico AC, Jorge AAL, McElreavey K, Mericq V, Merino PM, Palmert MR, Plummer L, Rey RA, Rezende RC, Seminara SB, Salnikov K, Banerjee I, Lam BYH, Perry JRB, Timpson NJ, Clayton P, Chan YM, Ong KK, O'Rahilly S. Duckett K, et al. Among authors: lam byh. J Clin Endocrinol Metab. 2023 Nov 17;108(12):e1580-e1587. doi: 10.1210/clinem/dgad373. J Clin Endocrinol Metab. 2023. PMID: 37339320 Free PMC article.
Loss-of-function mutations in the melanocortin 4 receptor in a UK birth cohort.
Wade KH, Lam BYH, Melvin A, Pan W, Corbin LJ, Hughes DA, Rainbow K, Chen JH, Duckett K, Liu X, Mokrosiński J, Mörseburg A, Neaves S, Williamson A, Zhang C, Farooqi IS, Yeo GSH, Timpson NJ, O'Rahilly S. Wade KH, et al. Among authors: lam byh. Nat Med. 2021 Jun;27(6):1088-1096. doi: 10.1038/s41591-021-01349-y. Epub 2021 May 27. Nat Med. 2021. PMID: 34045736 Free PMC article.
MC3R links nutritional state to childhood growth and the timing of puberty.
Lam BYH, Williamson A, Finer S, Day FR, Tadross JA, Gonçalves Soares A, Wade K, Sweeney P, Bedenbaugh MN, Porter DT, Melvin A, Ellacott KLJ, Lippert RN, Buller S, Rosmaninho-Salgado J, Dowsett GKC, Ridley KE, Xu Z, Cimino I, Rimmington D, Rainbow K, Duckett K, Holmqvist S, Khan A, Dai X, Bochukova EG; Genes & Health Research Team; Trembath RC, Martin HC, Coll AP, Rowitch DH, Wareham NJ, van Heel DA, Timpson N, Simerly RB, Ong KK, Cone RD, Langenberg C, Perry JRB, Yeo GS, O'Rahilly S. Lam BYH, et al. Nature. 2021 Nov;599(7885):436-441. doi: 10.1038/s41586-021-04088-9. Epub 2021 Nov 3. Nature. 2021. PMID: 34732894 Free PMC article.
Human embryonic genome activation initiates at the one-cell stage.
Asami M, Lam BYH, Ma MK, Rainbow K, Braun S, VerMilyea MD, Yeo GSH, Perry ACF. Asami M, et al. Among authors: lam byh. Cell Stem Cell. 2022 Feb 3;29(2):209-216.e4. doi: 10.1016/j.stem.2021.11.012. Epub 2021 Dec 21. Cell Stem Cell. 2022. PMID: 34936886 Free PMC article.
GDF15 linked to maternal risk of nausea and vomiting during pregnancy.
Fejzo M, Rocha N, Cimino I, Lockhart SM, Petry CJ, Kay RG, Burling K, Barker P, George AL, Yasara N, Premawardhena A, Gong S, Cook E, Rimmington D, Rainbow K, Withers DJ, Cortessis V, Mullin PM, MacGibbon KW, Jin E, Kam A, Campbell A, Polasek O, Tzoneva G, Gribble FM, Yeo GSH, Lam BYH, Saudek V, Hughes IA, Ong KK, Perry JRB, Sutton Cole A, Baumgarten M, Welsh P, Sattar N, Smith GCS, Charnock-Jones DS, Coll AP, Meek CL, Mettananda S, Hayward C, Mancuso N, O'Rahilly S. Fejzo M, et al. Among authors: lam byh. Nature. 2024 Jan;625(7996):760-767. doi: 10.1038/s41586-023-06921-9. Epub 2023 Dec 13. Nature. 2024. PMID: 38092039 Free PMC article.
Loss of GPR75 protects against non-alcoholic fatty liver disease and body fat accumulation.
Leeson-Payne A, Iyinikkel J, Malcolm C, Lam BYH, Sommer N, Dowsett GKC, Martinez de Morentin PB, Thompson D, Mackenzie A, Chianese R, Kentistou K, Gardner EJ, Perry JRB, Grassmann F, Speakman JR, Rochford JJ, Yeo GSH, Murray F, Heisler LK. Leeson-Payne A, et al. Among authors: lam byh. Cell Metab. 2024 May 7;36(5):1076-1087.e4. doi: 10.1016/j.cmet.2024.03.016. Epub 2024 Apr 22. Cell Metab. 2024. PMID: 38653246
A program of successive gene expression in mouse one-cell embryos.
Asami M, Lam BYH, Hoffmann M, Suzuki T, Lu X, Yoshida N, Ma MK, Rainbow K, Gužvić M, VerMilyea MD, Yeo GSH, Klein CA, Perry ACF. Asami M, et al. Among authors: lam byh. Cell Rep. 2023 Feb 28;42(2):112023. doi: 10.1016/j.celrep.2023.112023. Epub 2023 Jan 31. Cell Rep. 2023. PMID: 36729835 Free article.
Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.
Ramos-Pittol JM, Fernandes-Freitas I, Milona A, Manchishi SM, Rainbow K, Lam BYH, Tadross JA, Beucher A, Colledge WH, Cebola I, Murphy KG, Miguel-Aliaga I, Yeo GSH, Dhillo WS, Owen BM. Ramos-Pittol JM, et al. Among authors: lam byh. Nat Commun. 2023 May 29;14(1):3076. doi: 10.1038/s41467-023-38618-y. Nat Commun. 2023. PMID: 37248237 Free PMC article.
82 results