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B-cell-specific checkpoint molecules that regulate anti-tumour immunity.
Bod L, Kye YC, Shi J, Torlai Triglia E, Schnell A, Fessler J, Ostrowski SM, Von-Franque MY, Kuchroo JR, Barilla RM, Zaghouani S, Christian E, Delorey TM, Mohib K, Xiao S, Slingerland N, Giuliano CJ, Ashenberg O, Li Z, Rothstein DM, Fisher DE, Rozenblatt-Rosen O, Sharpe AH, Quintana FJ, Apetoh L, Regev A, Kuchroo VK. Bod L, et al. Among authors: quintana fj. Nature. 2023 Jul;619(7969):348-356. doi: 10.1038/s41586-023-06231-0. Epub 2023 Jun 21. Nature. 2023. PMID: 37344597 Free PMC article.
T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice.
Rodriguez-Manzanet R, Sanjuan MA, Wu HY, Quintana FJ, Xiao S, Anderson AC, Weiner HL, Green DR, Kuchroo VK. Rodriguez-Manzanet R, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8706-11. doi: 10.1073/pnas.0910359107. Epub 2010 Apr 5. Proc Natl Acad Sci U S A. 2010. PMID: 20368430 Free PMC article.
Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity.
Liu SM, Sutherland AP, Zhang Z, Rainbow DB, Quintana FJ, Paterson AM, Sharpe AH, Oukka M, Wicker LS, Kuchroo VK. Liu SM, et al. Among authors: quintana fj. J Immunol. 2012 Jan 1;188(1):155-62. doi: 10.4049/jimmunol.1102042. Epub 2011 Nov 28. J Immunol. 2012. PMID: 22124121 Free PMC article.
Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.
Xiao S, Brooks CR, Zhu C, Wu C, Sweere JM, Petecka S, Yeste A, Quintana FJ, Ichimura T, Sobel RA, Bonventre JV, Kuchroo VK. Xiao S, et al. Among authors: quintana fj. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12105-10. doi: 10.1073/pnas.1120914109. Epub 2012 Jul 5. Proc Natl Acad Sci U S A. 2012. PMID: 22773818 Free PMC article.
Induction and molecular signature of pathogenic TH17 cells.
Lee Y, Awasthi A, Yosef N, Quintana FJ, Xiao S, Peters A, Wu C, Kleinewietfeld M, Kunder S, Hafler DA, Sobel RA, Regev A, Kuchroo VK. Lee Y, et al. Among authors: quintana fj. Nat Immunol. 2012 Oct;13(10):991-9. doi: 10.1038/ni.2416. Epub 2012 Sep 9. Nat Immunol. 2012. PMID: 22961052 Free PMC article.
225 results