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[No title available]
[No authors listed] [No authors listed] PMID: 36782644
Discovery of a Potent Chloroacetamide GPX4 Inhibitor with Bioavailability to Enable Target Engagement in Mice, a Potential Tool Compound for Inducing Ferroptosis In Vivo.
Randolph JT, O'Connor MJ, Han F, Hutchins CW, Siu YA, Cho M, Zheng Y, Hickson JA, Markley JL, Manaves V, Algire M, Baker KA, Chapman AM, Gopalakrishnan SM, Panchal SC, Foster-Duke K, Stolarik DF, Kempf-Grote A, Dammeier D, Fossey S, Sun Q, Sun C, Shen Y, Dart MJ, Kati WM, Lai A, Firestone AJ, Kort ME. Randolph JT, et al. Among authors: markley jl. J Med Chem. 2023 Mar 23;66(6):3852-3865. doi: 10.1021/acs.jmedchem.2c01415. Epub 2023 Mar 6. J Med Chem. 2023. PMID: 36877935
Coordination of Di-Acetylated Histone Ligands by the ATAD2 Bromodomain.
Evans CM, Phillips M, Malone KL, Tonelli M, Cornilescu G, Cornilescu C, Holton SJ, Gorjánácz M, Wang L, Carlson S, Gay JC, Nix JC, Demeler B, Markley JL, Glass KC. Evans CM, et al. Among authors: markley jl. Int J Mol Sci. 2021 Aug 24;22(17):9128. doi: 10.3390/ijms22179128. Int J Mol Sci. 2021. PMID: 34502039 Free PMC article.
The Protein Data Bank Archive.
Velankar S, Burley SK, Kurisu G, Hoch JC, Markley JL. Velankar S, et al. Among authors: markley jl. Methods Mol Biol. 2021;2305:3-21. doi: 10.1007/978-1-0716-1406-8_1. Methods Mol Biol. 2021. PMID: 33950382 Review.
The BRPF1 bromodomain is a molecular reader of di-acetyllysine.
Obi JO, Lubula MY, Cornilescu G, Henrickson A, McGuire K, Evans CM, Phillips M, Boyson SP, Demeler B, Markley JL, Glass KC. Obi JO, et al. Among authors: markley jl. Curr Res Struct Biol. 2020;2:104-115. doi: 10.1016/j.crstbi.2020.05.001. Epub 2020 May 12. Curr Res Struct Biol. 2020. PMID: 33554132 Free PMC article.
493 results