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Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly.
Zürcher JF, Kleefeldt AA, Funke LFH, Birnbaum J, Fredens J, Grazioli S, Liu KC, Spinck M, Petris G, Murat P, Rehm FBH, Sale JE, Chin JW. Zürcher JF, et al. Among authors: petris g. Nature. 2023 Jul;619(7970):555-562. doi: 10.1038/s41586-023-06268-1. Epub 2023 Jun 28. Nature. 2023. PMID: 37380776 Free PMC article.
Mechanism-based traps enable protease and hydrolase substrate discovery.
Tang S, Beattie AT, Kafkova L, Petris G, Huguenin-Dezot N, Fiedler M, Freeman M, Chin JW. Tang S, et al. Among authors: petris g. Nature. 2022 Feb;602(7898):701-707. doi: 10.1038/s41586-022-04414-9. Epub 2022 Feb 16. Nature. 2022. PMID: 35173328 Free PMC article.
Synthetic genomics for curing genetic diseases.
Grazioli S, Petris G. Grazioli S, et al. Among authors: petris g. Prog Mol Biol Transl Sci. 2021;182:477-520. doi: 10.1016/bs.pmbts.2021.02.002. Epub 2021 Apr 9. Prog Mol Biol Transl Sci. 2021. PMID: 34175051
Refactored genetic codes enable bidirectional genetic isolation.
Zürcher JF, Robertson WE, Kappes T, Petris G, Elliott TS, Salmond GPC, Chin JW. Zürcher JF, et al. Among authors: petris g. Science. 2022 Nov 4;378(6619):516-523. doi: 10.1126/science.add8943. Epub 2022 Oct 20. Science. 2022. PMID: 36264827 Free PMC article.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice.
Prakasam R, Bonadiman A, Andreotti R, Zuccaro E, Dalfovo D, Marchioretti C, Tripathy D, Petris G, Anderson EN, Migazzi A, Tosatto L, Cereseto A, Battaglioli E, Sorarù G, Lim WF, Rinaldi C, Sambataro F, Pourshafie N, Grunseich C, Romanel A, Pandey UB, Contestabile A, Ronzitti G, Basso M, Pennuto M. Prakasam R, et al. Among authors: petris g. Nat Commun. 2023 Feb 6;14(1):603. doi: 10.1038/s41467-023-36186-9. Nat Commun. 2023. PMID: 36746939 Free PMC article.
A highly specific SpCas9 variant is identified by in vivo screening in yeast.
Casini A, Olivieri M, Petris G, Montagna C, Reginato G, Maule G, Lorenzin F, Prandi D, Romanel A, Demichelis F, Inga A, Cereseto A. Casini A, et al. Among authors: petris g. Nat Biotechnol. 2018 Mar;36(3):265-271. doi: 10.1038/nbt.4066. Epub 2018 Jan 29. Nat Biotechnol. 2018. PMID: 29431739 Free PMC article.
180 results