Arifi S - Search Results

1

Targeting the Alternative Vitamin E Metabolite Binding Site Enables Noncanonical PPARγ Modulation.

Arifi S, Marschner JA, Pollinger J, Isigkeit L, Heitel P, Kaiser A, Obeser L, Höfner G, Proschak E, Knapp S, Chaikuad A, Heering J, Merk D. Arifi S, et al. J Am Chem Soc. 2023 Jul 12;145(27):14802-14810. doi: 10.1021/jacs.3c03417. Epub 2023 Jun 29. J Am Chem Soc. 2023. PMID: 37385602 Free PMC article.

2

l-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARγ.

Gellrich L, Heitel P, Heering J, Kilu W, Pollinger J, Goebel T, Kahnt A, Arifi S, Pogoda W, Paulke A, Steinhilber D, Proschak E, Wurglics M, Schubert-Zsilavecz M, Chaikuad A, Knapp S, Bischoff I, Fürst R, Merk D. Gellrich L, et al. Among authors: arifi s. J Med Chem. 2020 Jul 9;63(13):6727-6740. doi: 10.1021/acs.jmedchem.9b02150. Epub 2020 Jun 4. J Med Chem. 2020. PMID: 32356658

3

The Medicinal Chemistry of Caffeine.

Faudone G, Arifi S, Merk D. Faudone G, et al. Among authors: arifi s. J Med Chem. 2021 Jun 10;64(11):7156-7178. doi: 10.1021/acs.jmedchem.1c00261. Epub 2021 May 21. J Med Chem. 2021. PMID: 34019396

4

Druggability Evaluation of the Neuron Derived Orphan Receptor (NOR-1) Reveals Inverse NOR-1 Agonists.

Zaienne D, Arifi S, Marschner JA, Heering J, Merk D. Zaienne D, et al. Among authors: arifi s. ChemMedChem. 2022 Aug 17;17(16):e202200259. doi: 10.1002/cmdc.202200259. Epub 2022 Jul 7. ChemMedChem. 2022. PMID: 35704774 Free PMC article.

5

Fragment-based discovery of orphan nuclear receptor Nur77/NGFI-B ligands.

Arifi S, Zaienne D, Heering J, Wein T, Zhubi R, Chaikuad A, Knapp S, Marschner JA, Merk D. Arifi S, et al. Bioorg Chem. 2022 Dec;129:106164. doi: 10.1016/j.bioorg.2022.106164. Epub 2022 Sep 17. Bioorg Chem. 2022. PMID: 36162288

6

Structural Fusion of Natural and Synthetic Ligand Features Boosts RXR Agonist Potency.

Adouvi G, Nawa F, Ballarotto M, Rüger LA, Knümann L, Kasch T, Arifi S, Schubert-Zsilavecz M, Willems S, Marschner JA, Pabel J, Merk D. Adouvi G, et al. Among authors: arifi s. J Med Chem. 2023 Dec 28;66(24):16762-16771. doi: 10.1021/acs.jmedchem.3c01435. Epub 2023 Dec 8. J Med Chem. 2023. PMID: 38064686

7

Rational design and virtual screening identify mimetics of the RXR agonist valerenic acid.

Isigkeit L, Kärcher A, Adouvi G, Arifi S, Merk D. Isigkeit L, et al. Among authors: arifi s. ChemMedChem. 2024 Mar 1;19(5):e202300379. doi: 10.1002/cmdc.202300379. Epub 2024 Jan 31. ChemMedChem. 2024. PMID: 38235922

8

Editorial: Precision medicine in sarcomas: the road to an effective biomarker-driven-care strategy.

Arifi S, Constantinidou A. Arifi S, et al. Front Oncol. 2023 Apr 5;13:1194593. doi: 10.3389/fonc.2023.1194593. eCollection 2023. Front Oncol. 2023. PMID: 37091172 Free PMC article. No abstract available.

9

Exploring the landscape of immunotherapy approaches in sarcomas.

Pilavaki P, Panagi M, Arifi S, Jones RL, Stylianopoulos T, Constantinidou A. Pilavaki P, et al. Among authors: arifi s. Front Oncol. 2023 Jan 9;12:1069963. doi: 10.3389/fonc.2022.1069963. eCollection 2022. Front Oncol. 2023. PMID: 36686827 Free PMC article. Review.

10

Molecular classification of soft tissue sarcomas for adequate diagnosis: A study on the northeast population of Morocco.

El Koubaiti R, Mazti A, Maaroufi M, El Idrissi M, El Ibrahimi A, El Mrini A, Bouhafa T, El Fakir S, Ouldim K, Arifi S, Chbani L. El Koubaiti R, et al. Among authors: arifi s. Heliyon. 2022 Sep 17;8(9):e10673. doi: 10.1016/j.heliyon.2022.e10673. eCollection 2022 Sep. Heliyon. 2022. PMID: 36164527 Free PMC article.

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