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Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau CA, Dubois SM, Buquicchio FA, Hsieh YH, Garg K, Kautz P, Nitsch L, Praktiknjo SD, Maschmeyer P, Verboon JM, Gutierrez JC, Yin Y, Fiskin E, Luo W, Mimitou EP, Muus C, Malhotra R, Parikh S, Fleming MD, Oevermann L, Schulte J, Eckert C, Kundaje A, Smibert P, Vardhana SA, Satpathy AT, Regev A, Sankaran VG, Agarwal S, Ludwig LS. Lareau CA, et al. Among authors: fleming md. Nat Genet. 2023 Jul;55(7):1198-1209. doi: 10.1038/s41588-023-01433-8. Epub 2023 Jun 29. Nat Genet. 2023. PMID: 37386249 Free PMC article.
Induced pluripotent stem cells with a mitochondrial DNA deletion.
Cherry AB, Gagne KE, McLoughlin EM, Baccei A, Gorman B, Hartung O, Miller JD, Zhang J, Zon RL, Ince TA, Neufeld EJ, Lerou PH, Fleming MD, Daley GQ, Agarwal S. Cherry AB, et al. Among authors: fleming md. Stem Cells. 2013 Jul;31(7):1287-97. doi: 10.1002/stem.1354. Stem Cells. 2013. PMID: 23400930 Free PMC article.
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, Zon LI. Donovan A, et al. Among authors: fleming md. Nature. 2000 Feb 17;403(6771):776-81. doi: 10.1038/35001596. Nature. 2000. PMID: 10693807
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA).
Finberg KE, Heeney MM, Campagna DR, Aydinok Y, Pearson HA, Hartman KR, Mayo MM, Samuel SM, Strouse JJ, Markianos K, Andrews NC, Fleming MD. Finberg KE, et al. Among authors: fleming md. Nat Genet. 2008 May;40(5):569-71. doi: 10.1038/ng.130. Epub 2008 Apr 13. Nat Genet. 2008. PMID: 18408718 Free PMC article.
259 results