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Single-cell multi-omics of mitochondrial DNA disorders reveals dynamics of purifying selection across human immune cells.
Lareau CA, Dubois SM, Buquicchio FA, Hsieh YH, Garg K, Kautz P, Nitsch L, Praktiknjo SD, Maschmeyer P, Verboon JM, Gutierrez JC, Yin Y, Fiskin E, Luo W, Mimitou EP, Muus C, Malhotra R, Parikh S, Fleming MD, Oevermann L, Schulte J, Eckert C, Kundaje A, Smibert P, Vardhana SA, Satpathy AT, Regev A, Sankaran VG, Agarwal S, Ludwig LS. Lareau CA, et al. Among authors: vardhana sa. Nat Genet. 2023 Jul;55(7):1198-1209. doi: 10.1038/s41588-023-01433-8. Epub 2023 Jun 29. Nat Genet. 2023. PMID: 37386249 Free PMC article.
CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer.
Bange EM, Han NA, Wileyto P, Kim JY, Gouma S, Robinson J, Greenplate AR, Hwee MA, Porterfield F, Owoyemi O, Naik K, Zheng C, Galantino M, Weisman AR, Ittner CAG, Kugler EM, Baxter AE, Oniyide O, Agyekum RS, Dunn TG, Jones TK, Giannini HM, Weirick ME, McAllister CM, Babady NE, Kumar A, Widman AJ, DeWolf S, Boutemine SR, Roberts C, Budzik KR, Tollett S, Wright C, Perloff T, Sun L, Mathew D, Giles JR, Oldridge DA, Wu JE, Alanio C, Adamski S, Garfall AL, Vella LA, Kerr SJ, Cohen JV, Oyer RA, Massa R, Maillard IP, Maxwell KN, Reilly JP, Maslak PG, Vonderheide RH, Wolchok JD, Hensley SE, Wherry EJ, Meyer NJ, DeMichele AM, Vardhana SA, Mamtani R, Huang AC. Bange EM, et al. Among authors: vardhana sa. Nat Med. 2021 Jul;27(7):1280-1289. doi: 10.1038/s41591-021-01386-7. Epub 2021 May 20. Nat Med. 2021. PMID: 34017137 Free PMC article.
Glutamine independence is a selectable feature of pluripotent stem cells.
Vardhana SA, Arnold PK, Rosen BP, Chen Y, Carey BW, Huangfu D, Carmona Fontaine C, Thompson CB, Finley LWS. Vardhana SA, et al. Nat Metab. 2019 Jul;1(7):676-687. doi: 10.1038/s42255-019-0082-3. Epub 2019 Jul 8. Nat Metab. 2019. PMID: 31511848 Free PMC article.
The many faces of the anti-COVID immune response.
Vardhana SA, Wolchok JD. Vardhana SA, et al. J Exp Med. 2020 Jun 1;217(6):e20200678. doi: 10.1084/jem.20200678. J Exp Med. 2020. PMID: 32353870 Free PMC article.
Challenges and opportunities in 2021.
Akkari L, Finley SD, Ho PC, Jenkins M, Maier BB, McGranahan N, Mutebi M, Perera RM, Robles-Espinoza CD, Vardhana S, Wan L, Xu MM. Akkari L, et al. Nat Cancer. 2021 Dec;2(12):1278-1283. doi: 10.1038/s43018-021-00294-6. Nat Cancer. 2021. PMID: 35121916 No abstract available.
Metabolic regulation of the cancer-immunity cycle.
Somarribas Patterson LF, Vardhana SA. Somarribas Patterson LF, et al. Among authors: vardhana sa. Trends Immunol. 2021 Nov;42(11):975-993. doi: 10.1016/j.it.2021.09.002. Epub 2021 Oct 2. Trends Immunol. 2021. PMID: 34610889 Free PMC article. Review.
43 results