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Long-range DNA end resection supports homologous recombination by checkpoint activation rather than extensive homology generation.
Elife. 2023 Jun 30;12:e84322. doi: 10.7554/eLife.84322.
Elife. 2023.
PMID: 37387287
Free PMC article.
Genetic reporters to detect and quantify homologous recombination in yeast.
Marie L, Kimble MT, Symington LS.
Marie L, et al. Among authors: kimble mt.
Methods Cell Biol. 2024;182:35-48. doi: 10.1016/bs.mcb.2022.10.011. Epub 2022 Nov 28.
Methods Cell Biol. 2024.
PMID: 38359986
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An in vivo method for diversifying the functions of therapeutic antibodies.
Tian M, Cheng HL, Kimble MT, McGovern K, Waddicor P, Chen Y, Cantor E, Qiu M, Tuchel ME, Dao M, Alt FW.
Tian M, et al. Among authors: kimble mt.
Proc Natl Acad Sci U S A. 2021 Mar 9;118(10):e2025596118. doi: 10.1073/pnas.2025596118.
Proc Natl Acad Sci U S A. 2021.
PMID: 33658386
Free PMC article.
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Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models.
Tian M, McGovern K, Cheng HL, Waddicor P, Rieble L, Dao M, Chen Y, Kimble MT, Cantor E, Manfredonia N, Judson R, Chapdelaine-Williams A, Cain DW, Haynes BF, Alt FW.
Tian M, et al. Among authors: kimble mt.
Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7929-7940. doi: 10.1073/pnas.1921996117. Epub 2020 Mar 24.
Proc Natl Acad Sci U S A. 2020.
PMID: 32209668
Free PMC article.
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Sae2 antagonizes Rad9 accumulation at DNA double-strand breaks to attenuate checkpoint signaling and facilitate end resection.
Yu TY, Kimble MT, Symington LS.
Yu TY, et al. Among authors: kimble mt.
Proc Natl Acad Sci U S A. 2018 Dec 18;115(51):E11961-E11969. doi: 10.1073/pnas.1816539115. Epub 2018 Dec 3.
Proc Natl Acad Sci U S A. 2018.
PMID: 30510002
Free PMC article.
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