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Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis.
Brown AC, Cohen CJ, Mielczarek O, Migliorini G, Costantino F, Allcock A, Davidson C, Elliott KS, Fang H, Lledó Lara A, Martin AC, Osgood JA, Sanniti A, Scozzafava G, Vecellio M, Zhang P, Black MH, Li S, Truong D, Molineros J, Howe T, Wordsworth BP, Bowness P, Knight JC. Brown AC, et al. Among authors: mielczarek o. Cell Genom. 2023 Apr 24;3(6):100306. doi: 10.1016/j.xgen.2023.100306. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388915 Free PMC article.
Using de novo assembly to identify structural variation of eight complex immune system gene regions.
Zhang JY, Roberts H, Flores DSC, Cutler AJ, Brown AC, Whalley JP, Mielczarek O, Buck D, Lockstone H, Xella B, Oliver K, Corton C, Betteridge E, Bashford-Rogers R, Knight JC, Todd JA, Band G. Zhang JY, et al. Among authors: mielczarek o. PLoS Comput Biol. 2021 Aug 3;17(8):e1009254. doi: 10.1371/journal.pcbi.1009254. eCollection 2021 Aug. PLoS Comput Biol. 2021. PMID: 34343164 Free PMC article.
Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus.
Downes DJ, Cross AR, Hua P, Roberts N, Schwessinger R, Cutler AJ, Munis AM, Brown J, Mielczarek O, de Andrea CE, Melero I; COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium; Gill DR, Hyde SC, Knight JC, Todd JA, Sansom SN, Issa F, Davies JOJ, Hughes JR. Downes DJ, et al. Among authors: mielczarek o. Nat Genet. 2021 Nov;53(11):1606-1615. doi: 10.1038/s41588-021-00955-3. Epub 2021 Nov 4. Nat Genet. 2021. PMID: 34737427 Free PMC article.
Intra- and interchromosomal contact mapping reveals the Igh locus has extensive conformational heterogeneity and interacts with B-lineage genes.
Mielczarek O, Rogers CH, Zhan Y, Matheson LS, Stubbington MJT, Schoenfelder S, Bolland DJ, Javierre BM, Wingett SW, Várnai C, Segonds-Pichon A, Conn SJ, Krueger F, Andrews S, Fraser P, Giorgetti L, Corcoran AE. Mielczarek O, et al. Cell Rep. 2023 Sep 26;42(9):113074. doi: 10.1016/j.celrep.2023.113074. Epub 2023 Sep 6. Cell Rep. 2023. PMID: 37676766 Free PMC article.
Recurrent Orbital Inflammation Due to Fibrous Dysplasia.
Malec K, Miszczyk J, Brzewski P, Dobosz P, Mielczarek O. Malec K, et al. Among authors: mielczarek o. Facial Plast Surg. 2017 Feb;33(1):112-113. doi: 10.1055/s-0037-1598075. Epub 2017 Feb 22. Facial Plast Surg. 2017. PMID: 28226381 No abstract available.