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Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis.
Brown AC, Cohen CJ, Mielczarek O, Migliorini G, Costantino F, Allcock A, Davidson C, Elliott KS, Fang H, Lledó Lara A, Martin AC, Osgood JA, Sanniti A, Scozzafava G, Vecellio M, Zhang P, Black MH, Li S, Truong D, Molineros J, Howe T, Wordsworth BP, Bowness P, Knight JC. Brown AC, et al. Among authors: vecellio m. Cell Genom. 2023 Apr 24;3(6):100306. doi: 10.1016/j.xgen.2023.100306. eCollection 2023 Jun 14. Cell Genom. 2023. PMID: 37388915 Free PMC article.
An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation.
Roberts AR, Vecellio M, Chen L, Ridley A, Cortes A, Knight JC, Bowness P, Cohen CJ, Wordsworth BP. Roberts AR, et al. Among authors: vecellio m. Ann Rheum Dis. 2016 Dec;75(12):2150-2156. doi: 10.1136/annrheumdis-2015-208640. Epub 2016 Feb 25. Ann Rheum Dis. 2016. PMID: 26916345 Free PMC article.
The severity of ankylosing spondylitis and responses to anti-tumour necrosis factor biologics are not influenced by the tumour necrosis factor receptor polymorphism incriminated in multiple sclerosis.
Watts L, Karaderi T, Roberts A, Appleton L, Wordsworth T, Cohen C, Wordsworth P, Vecellio M. Watts L, et al. Among authors: vecellio m. Genes Immun. 2019 Feb;20(2):167-171. doi: 10.1038/s41435-018-0017-0. Epub 2018 Mar 10. Genes Immun. 2019. PMID: 29535371
46 results