Okamoto H - Search Results

1

Impact of an SLC30A8 loss-of-function variant on the pancreatic distribution of zinc and manganese: laser ablation-ICP-MS and positron emission tomography studies in mice.

Firth G, Georgiadou E, Griffiths A, Amrahli M, Kim J, Yu Z, Hu M, Stewart TJ, Leclerc I, Okamoto H, Gomez D, Blower PJ, Rutter GA. Firth G, et al. Among authors: okamoto h. Front Endocrinol (Lausanne). 2023 Jun 16;14:1171933. doi: 10.3389/fendo.2023.1171933. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37396167 Free PMC article.

2

Single-Cell RNAseq Reveals That Pancreatic β-Cells From Very Old Male Mice Have a Young Gene Signature.

Xin Y, Okamoto H, Kim J, Ni M, Adler C, Cavino K, Na E, Murphy AJ, Yancopoulos GD, Lin C, Gromada J. Xin Y, et al. Among authors: okamoto h. Endocrinology. 2016 Sep;157(9):3431-8. doi: 10.1210/en.2016-1235. Epub 2016 Jul 28. Endocrinology. 2016. PMID: 27466694

3

Glucagon Receptor Blockade With a Human Antibody Normalizes Blood Glucose in Diabetic Mice and Monkeys.

Okamoto H, Kim J, Aglione J, Lee J, Cavino K, Na E, Rafique A, Kim JH, Harp J, Valenzuela DM, Yancopoulos GD, Murphy AJ, Gromada J. Okamoto H, et al. Endocrinology. 2015 Aug;156(8):2781-94. doi: 10.1210/en.2015-1011. Epub 2015 May 28. Endocrinology. 2015. PMID: 26020795

4

Loss of SFRP4 Alters Body Size, Food Intake, and Energy Expenditure in Diet-Induced Obese Male Mice.

Mastaitis J, Eckersdorff M, Min S, Xin Y, Cavino K, Aglione J, Okamoto H, Na E, Stitt T, Dominguez MG, Schmahl JP, Lin C, Gale NW, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gromada J. Mastaitis J, et al. Among authors: okamoto h. Endocrinology. 2015 Dec;156(12):4502-10. doi: 10.1210/en.2015-1257. Epub 2015 Sep 25. Endocrinology. 2015. PMID: 26406932

5

Gene Signature of Proliferating Human Pancreatic α Cells.

Dominguez Gutierrez G, Xin Y, Okamoto H, Kim J, Lee AH, Ni M, Adler C, Yancopoulos GD, Murphy AJ, Gromada J. Dominguez Gutierrez G, et al. Among authors: okamoto h. Endocrinology. 2018 Sep 1;159(9):3177-3186. doi: 10.1210/en.2018-00469. Endocrinology. 2018. PMID: 30010845

6

[No title available]

[No authors listed] [No authors listed] PMID: 33513617

7

Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition.

Kim J, Dominguez Gutierrez G, Xin Y, Cavino K, Sung B, Sipos B, Kloeppel G, Gromada J, Okamoto H. Kim J, et al. Among authors: okamoto h. Endocrinology. 2019 May 1;160(5):979-988. doi: 10.1210/en.2019-00022. Endocrinology. 2019. PMID: 30938753

8

Glucagon Receptor Inhibition Reduces Hyperammonemia and Lethality in Male Mice with Urea Cycle Disorder.

Cavino K, Sung B, Su Q, Na E, Kim J, Cheng X, Gromada J, Okamoto H. Cavino K, et al. Among authors: okamoto h. Endocrinology. 2021 Jan 1;162(1):bqaa211. doi: 10.1210/endocr/bqaa211. Endocrinology. 2021. PMID: 33206168

9

RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes.

Xin Y, Kim J, Okamoto H, Ni M, Wei Y, Adler C, Murphy AJ, Yancopoulos GD, Lin C, Gromada J. Xin Y, et al. Among authors: okamoto h. Cell Metab. 2016 Oct 11;24(4):608-615. doi: 10.1016/j.cmet.2016.08.018. Epub 2016 Sep 22. Cell Metab. 2016. PMID: 27667665 Free article.

10

Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.

Okamoto H, Cavino K, Na E, Krumm E, Kim SY, Cheng X, Murphy AJ, Yancopoulos GD, Gromada J. Okamoto H, et al. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2753-2758. doi: 10.1073/pnas.1621069114. Epub 2017 Jan 23. Proc Natl Acad Sci U S A. 2017. PMID: 28115707 Free PMC article.

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