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The unusual gene architecture of polyubiquitin is created by dual-specific splice sites.
Genome Biol. 2024 Jan 24;25(1):33. doi: 10.1186/s13059-023-03157-8.
Genome Biol. 2024.
PMID: 38268025
Free PMC article.
Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
Clark NE, Katolik A, Gallant P, Welch A, Murphy E, Buerer L, Schorl C, Naik N, Naik MT, Holloway SP, Cano K, Weintraub ST, Howard KM, Hart PJ, Jogl G, Damha MJ, Fairbrother WG.
Clark NE, et al. Among authors: buerer l.
J Biol Chem. 2023 Sep;299(9):105100. doi: 10.1016/j.jbc.2023.105100. Epub 2023 Jul 26.
J Biol Chem. 2023.
PMID: 37507019
Free PMC article.
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The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG.
Buerer L, et al.
Res Sq [Preprint]. 2023 Jun 13:rs.3.rs-2931976. doi: 10.21203/rs.3.rs-2931976/v1.
Res Sq. 2023.
PMID: 37398028
Free PMC article.
Preprint.
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A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy.
Townley BA, Buerer L, Tsao N, Bacolla A, Mansoori F, Rusanov T, Clark N, Goodarzi N, Schmidt N, Srivatsan SN, Sun H, Sample RA, Brickner JR, McDonald D, Tsai MS, Walter MJ, Wozniak DF, Holehouse AS, Pena V, Tainer JA, Fairbrother WG, Mosammaparast N.
Townley BA, et al. Among authors: buerer l.
Mol Cell. 2023 Jul 6;83(13):2258-2275.e11. doi: 10.1016/j.molcel.2023.06.011. Epub 2023 Jun 26.
Mol Cell. 2023.
PMID: 37369199
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Metal content and kinetic properties of yeast RNA lariat debranching enzyme Dbr1.
Clark NE, Katolik A, Taggart AJ, Buerer L, Holloway SP, Miller N, Phillips JD, Farrell CP, Damha MJ, Fairbrother WG.
Clark NE, et al. Among authors: buerer l.
RNA. 2022 Jul;28(7):927-936. doi: 10.1261/rna.079159.122. Epub 2022 Apr 22.
RNA. 2022.
PMID: 35459748
Free PMC article.
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Massively parallel reporter assays discover de novo exonic splicing mutants in paralogs of Autism genes.
Rhine CL, Neil C, Wang J, Maguire S, Buerer L, Salomon M, Meremikwu IC, Kim J, Strande NT, Fairbrother WG.
Rhine CL, et al. Among authors: buerer l.
PLoS Genet. 2022 Jan 20;18(1):e1009884. doi: 10.1371/journal.pgen.1009884. eCollection 2022 Jan.
PLoS Genet. 2022.
PMID: 35051175
Free PMC article.
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Efficient Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Exhaled Breath.
Duan C, Buerer L, Wang J, Kaplan S, Sabalewski G, Jay GD, Monaghan SF, Arena AE, Fairbrother WG.
Duan C, et al. Among authors: buerer l.
J Mol Diagn. 2021 Dec;23(12):1661-1670. doi: 10.1016/j.jmoldx.2021.09.005. Epub 2021 Sep 29.
J Mol Diagn. 2021.
PMID: 34600137
Free PMC article.
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Mutational bias and the protein code shape the evolution of splicing enhancers.
Rong S, Buerer L, Rhine CL, Wang J, Cygan KJ, Fairbrother WG.
Rong S, et al. Among authors: buerer l.
Nat Commun. 2020 Jun 5;11(1):2845. doi: 10.1038/s41467-020-16673-z.
Nat Commun. 2020.
PMID: 32504065
Free PMC article.
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