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Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain.
Clark NE, Katolik A, Gallant P, Welch A, Murphy E, Buerer L, Schorl C, Naik N, Naik MT, Holloway SP, Cano K, Weintraub ST, Howard KM, Hart PJ, Jogl G, Damha MJ, Fairbrother WG. Clark NE, et al. Among authors: katolik a. J Biol Chem. 2023 Sep;299(9):105100. doi: 10.1016/j.jbc.2023.105100. Epub 2023 Jul 26. J Biol Chem. 2023. PMID: 37507019 Free PMC article.
The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.
Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG. Buerer L, et al. Among authors: katolik a. Res Sq [Preprint]. 2023 Jun 13:rs.3.rs-2931976. doi: 10.21203/rs.3.rs-2931976/v1. Res Sq. 2023. PMID: 37398028 Free PMC article. Preprint.
Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference.
Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Habibian M, et al. Among authors: katolik a. Nucleic Acids Res. 2020 May 21;48(9):4643-4657. doi: 10.1093/nar/gkaa222. Nucleic Acids Res. 2020. PMID: 32282904 Free PMC article.
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