Staley JP - Search Results

1

Global impact of aberrant splicing on human gene expression levels.

Fair B, Najar CBA, Zhao J, Lozano S, Reilly A, Mossian G, Staley JP, Wang J, Li YI. Fair B, et al. Among authors: staley jp. bioRxiv [Preprint]. 2023 Oct 16:2023.09.13.557588. doi: 10.1101/2023.09.13.557588. bioRxiv. 2023. PMID: 37745605 Free PMC article. Preprint.

2

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.

Buerer L, Clark NE, Welch A, Duan C, Taggart AJ, Townley BA, Wang J, Soemedi R, Rong S, Lin CL, Zeng Y, Katolik A, Staley JP, Damha MJ, Mosammaparast N, Fairbrother WG. Buerer L, et al. Among authors: staley jp. Res Sq [Preprint]. 2023 Jun 13:rs.3.rs-2931976. doi: 10.21203/rs.3.rs-2931976/v1. Res Sq. 2023. PMID: 37398028 Free PMC article. Preprint.

3

Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing.

Zeng Y, Fair BJ, Zeng H, Krishnamohan A, Hou Y, Hall JM, Ruthenburg AJ, Li YI, Staley JP. Zeng Y, et al. Among authors: staley jp. Mol Cell. 2022 Dec 15;82(24):4681-4699.e8. doi: 10.1016/j.molcel.2022.11.004. Epub 2022 Nov 25. Mol Cell. 2022. PMID: 36435176 Free PMC article.

4

Termination of pre-mRNA splicing requires that the ATPase and RNA unwindase Prp43p acts on the catalytic snRNA U6.

Toroney R, Nielsen KH, Staley JP. Toroney R, et al. Among authors: staley jp. Genes Dev. 2019 Nov 1;33(21-22):1555-1574. doi: 10.1101/gad.328294.119. Epub 2019 Sep 26. Genes Dev. 2019. PMID: 31558568 Free PMC article.

5

Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA.

He Y, Staley JP, Andersen GR, Nielsen KH. He Y, et al. Among authors: staley jp. RNA. 2017 Jul;23(7):1110-1124. doi: 10.1261/rna.060954.117. Epub 2017 Apr 17. RNA. 2017. PMID: 28416566 Free PMC article.

6

Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.

Shao Y, Huang H, Qin D, Li NS, Koide A, Staley JP, Koide S, Kossiakoff AA, Piccirilli JA. Shao Y, et al. Among authors: staley jp. J Mol Biol. 2016 Oct 9;428(20):4100-4114. doi: 10.1016/j.jmb.2016.08.029. Epub 2016 Sep 2. J Mol Biol. 2016. PMID: 27593161 Free PMC article.

7

The Evolutionarily-conserved Polyadenosine RNA Binding Protein, Nab2, Cooperates with Splicing Machinery to Regulate the Fate of pre-mRNA.

Soucek S, Zeng Y, Bellur DL, Bergkessel M, Morris KJ, Deng Q, Duong D, Seyfried NT, Guthrie C, Staley JP, Fasken MB, Corbett AH. Soucek S, et al. Among authors: staley jp. Mol Cell Biol. 2016 Nov;36(21):2697-2714. doi: 10.1128/MCB.00402-16. Epub 2016 Aug 15. Mol Cell Biol. 2016. PMID: 27528618 Free PMC article.

8

Reverse transcriptases lend a hand in splicing catalysis.

Piccirilli JA, Staley JP. Piccirilli JA, et al. Among authors: staley jp. Nat Struct Mol Biol. 2016 Jun 7;23(6):507-9. doi: 10.1038/nsmb.3242. Nat Struct Mol Biol. 2016. PMID: 27273636 Free PMC article.

9

Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.

Ranoa DR, Parekh AD, Pitroda SP, Huang X, Darga T, Wong AC, Huang L, Andrade J, Staley JP, Satoh T, Akira S, Weichselbaum RR, Khodarev NN. Ranoa DR, et al. Among authors: staley jp. Oncotarget. 2016 May 3;7(18):26496-515. doi: 10.18632/oncotarget.8420. Oncotarget. 2016. PMID: 27034163 Free PMC article.

10

Spliceosomal DEAH-Box ATPases Remodel Pre-mRNA to Activate Alternative Splice Sites.

Semlow DR, Blanco MR, Walter NG, Staley JP. Semlow DR, et al. Among authors: staley jp. Cell. 2016 Feb 25;164(5):985-98. doi: 10.1016/j.cell.2016.01.025. Cell. 2016. PMID: 26919433 Free PMC article.

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