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Page 1
Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.
Klepper A, Kung A, Vazquez SE, Mitchell A, Mann S, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai J, Weiler-Normann C, Lohse AW, DeRisi J, Tana M. Klepper A, et al. Among authors: derisi j. medRxiv [Preprint]. 2023 Jun 27:2023.06.12.23291297. doi: 10.1101/2023.06.12.23291297. medRxiv. 2023. PMID: 37398174 Free PMC article. Preprint.
Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19: Anti-IFN antibodies in critical COVID-19 correlate with poor ISG response and upregulation of LAIR1 surface protein in PBMCs.
van der Wijst MGP, Vazquez SE, Hartoularos GC, Bastard P, Grant T, Bueno R, Lee DS, Greenland JR, Sun Y, Perez R, Ogorodnikov A, Ward A, Mann SA, Lynch KL, Yun C, Havlir DV, Chamie G, Marquez C, Greenhouse B, Lionakis MS, Norris PJ, Dumont LJ, Kelly K, Zhang P, Zhang Q, Gervais A, Le Voyer T, Whatley A, Si Y, Byrne A, Combes AJ, Rao AA, Song YS; UCSF COMET consortium; Fragiadakis GK, Kangelaris K, Calfee CS, Erle DJ, Hendrickson C, Krummel MF, Woodruff PG, Langelier CR, Casanova JL, Derisi JL, Anderson MS, Ye CJ. van der Wijst MGP, et al. Among authors: derisi jl. bioRxiv [Preprint]. 2021 Mar 10:2021.03.09.434529. doi: 10.1101/2021.03.09.434529. bioRxiv. 2021. PMID: 33758859 Free PMC article. Preprint.
SARS-CoV-2 variant exposures elicit antibody responses with differential cross-neutralization of established and emerging strains including Delta and Omicron.
Laurie MT, Liu J, Sunshine S, Peng J, Black D, Mitchell AM, Mann SA, Pilarowski G, Zorn KC, Rubio L, Bravo S, Marquez C, Sabatino JJ Jr, Mittl K, Petersen M, Havlir D, DeRisi J. Laurie MT, et al. Among authors: derisi j. medRxiv [Preprint]. 2021 Dec 22:2021.09.08.21263095. doi: 10.1101/2021.09.08.21263095. medRxiv. 2021. PMID: 34981075 Free PMC article. Updated. Preprint.
Autoantigen profiling reveals a shared post-COVID signature in fully recovered and Long COVID patients.
Bodansky A, Wang CY, Saxena A, Mitchell A, Takahashi S, Anglin K, Huang B, Hoh R, Lu S, Goldberg SA, Romero J, Tran B, Kirtikar R, Grebe H, So M, Greenhouse B, Durstenfeld MS, Hsue PY, Hellmuth J, Kelly JD, Martin JN, Anderson MS, Deeks SG, Henrich TJ, DeRisi JL, Peluso MJ. Bodansky A, et al. Among authors: derisi jl. medRxiv [Preprint]. 2023 Feb 9:2023.02.06.23285532. doi: 10.1101/2023.02.06.23285532. medRxiv. 2023. PMID: 36798288 Free PMC article. Updated. Preprint.
Validation of a murine proteome-wide phage display library for the identification of autoantibody specificities.
Rackaityte E, Proekt I, Miller HS, Ramesh A, Brooks JF, Kung AF, Mandel-Brehm C, Yu D, Zamecnik C, Bair R, Vazquez SE, Sunshine S, Abram CL, Lowell CA, Rizzuto G, Wilson MR, Zikherman J, Anderson MS, DeRisi JL. Rackaityte E, et al. Among authors: derisi jl. bioRxiv [Preprint]. 2023 Apr 7:2023.04.07.535899. doi: 10.1101/2023.04.07.535899. bioRxiv. 2023. PMID: 37066405 Free PMC article. Updated. Preprint.
A Predictive Autoantibody Signature in Multiple Sclerosis.
Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Tubati A, Gomez R, Fouassier C, Gerungan C, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BA, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR. Zamecnik CR, et al. Among authors: derisi jl. medRxiv [Preprint]. 2023 May 15:2023.05.01.23288943. doi: 10.1101/2023.05.01.23288943. medRxiv. 2023. PMID: 37205595 Free PMC article. Updated. Preprint.
Antigenic responses are hallmarks of fibrotic interstitial lung diseases independent of underlying etiologies.
Yoon YM, Velez TE, Upadhyay V, Vazquez SE, Lee CT, Selvan KC, Law CS, Blaine KM, Hollinger MK, Decker DC, Clark MR, Strek ME, Guzy RD, Adegunsoye A, Noth I, Wolters PJ, Anderson M, DeRisi JL, Shum AK, Sperling AI. Yoon YM, et al. Among authors: derisi jl. medRxiv [Preprint]. 2023 May 11:2023.05.08.23289640. doi: 10.1101/2023.05.08.23289640. medRxiv. 2023. PMID: 37214861 Free PMC article. Preprint.
Pulmonary microbiome and transcriptome signatures reveal distinct pathobiologic states associated with mortality in two cohorts of pediatric stem cell transplant patients.
Zinter MS, Dvorak CC, Mayday MY, Reyes G, Simon MR, Pearce EM, Kim H, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Godder K, Duncan CN, Lalefar NR, Kreml EM, Hume JR, Abdel-Azim H, Hurley C, Cuvelier GDE, Keating AK, Qayed M, Killinger JS, Fitzgerald JC, Hanna R, Mahadeo KM, Quigg TC, Satwani P, Castillo P, Gertz SJ, Moore TB, Hanisch B, Abdel-Mageed A, Phelan R, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Sulaiman I, Segal LN, Versluys BA, Lindemans CA, Boelens JJ, DeRisi JL; Pediatric Transplantation and Cell Therapy Consortium. Zinter MS, et al. Among authors: derisi jl. medRxiv [Preprint]. 2023 Nov 29:2023.11.29.23299130. doi: 10.1101/2023.11.29.23299130. medRxiv. 2023. PMID: 38077035 Free PMC article. Preprint.
Unveiling the autoreactome: Proteome-wide immunological fingerprints reveal the promise of plasma cell depleting therapy.
Bodansky A, Yu DJ, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green DJ, Gauthier J, Turtle CJ, Zorn K, O'Donovan B, Mandel-Brehm C, Asaki J, Kortbawi H, Kung AF, Rackaityte E, Wang CY, Saxena A, de Dios K, Masi G, Nowak RJ, O'Connor KC, Li H, Diaz VE, Casaletto KB, Gontrum EQ, Chan B, Kramer JH, Wilson MR, Utz PJ, Hill JA, Jackson SW, Anderson MS, DeRisi JL. Bodansky A, et al. Among authors: derisi jl. medRxiv [Preprint]. 2023 Dec 20:2023.12.19.23300188. doi: 10.1101/2023.12.19.23300188. medRxiv. 2023. PMID: 38196603 Free PMC article. Preprint.
An autoantibody signature predictive for multiple sclerosis.
Zamecnik CR, Sowa GM, Abdelhak A, Dandekar R, Bair RD, Wade KJ, Bartley CM, Kizer K, Augusto DG, Tubati A, Gomez R, Fouassier C, Gerungan C, Caspar CM, Alexander J, Wapniarski AE, Loudermilk RP, Eggers EL, Zorn KC, Ananth K, Jabassini N, Mann SA, Ragan NR, Santaniello A, Henry RG, Baranzini SE, Zamvil SS, Sabatino JJ Jr, Bove RM, Guo CY, Gelfand JM, Cuneo R, von Büdingen HC, Oksenberg JR, Cree BAC, Hollenbach JA, Green AJ, Hauser SL, Wallin MT, DeRisi JL, Wilson MR. Zamecnik CR, et al. Among authors: derisi jl. Nat Med. 2024 May;30(5):1300-1308. doi: 10.1038/s41591-024-02938-3. Epub 2024 Apr 19. Nat Med. 2024. PMID: 38641750
376 results