Klepper A - Search Results

1

Novel autoantibody targets identified in patients with autoimmune hepatitis (AIH) by PhIP-Seq reveals pathogenic insights.

Klepper A, Kung A, Vazquez SE, Mitchell A, Mann S, Zorn K, Avila-Vargas I, Kari S, Tekeste M, Castro J, Lee B, Duarte M, Khalili M, Yang M, Wolters P, Price J, Perito E, Feng S, Maher JJ, Lai J, Weiler-Normann C, Lohse AW, DeRisi J, Tana M. Klepper A, et al. medRxiv [Preprint]. 2023 Jun 27:2023.06.12.23291297. doi: 10.1101/2023.06.12.23291297. medRxiv. 2023. PMID: 37398174 Free PMC article. Preprint.

2

Transcriptomic profiling of blood from autoimmune hepatitis patients reveals potential mechanisms with implications for management.

Tana MM, Klepper A, Lyden A, Pisco AO, Phelps M, McGee B, Green K, Feng S, DeRisi J, Crawford ED, Lammert CS. Tana MM, et al. Among authors: klepper a. PLoS One. 2022 Mar 21;17(3):e0264307. doi: 10.1371/journal.pone.0264307. eCollection 2022. PLoS One. 2022. PMID: 35312680 Free PMC article.

3

A subset of liver resident natural killer cells is expanded in hepatitis C-infected patients with better liver function.

Doyle EH, Aloman C, El-Shamy A, Eng F, Rahman A, Klepper AL, Haydel B, Florman SS, Fiel MI, Schiano T, Branch AD. Doyle EH, et al. Among authors: klepper al. Sci Rep. 2021 Jan 15;11(1):1551. doi: 10.1038/s41598-020-80819-8. Sci Rep. 2021. PMID: 33452360 Free PMC article.

4

Individual liver plasmacytoid dendritic cells are capable of producing IFNα and multiple additional cytokines during chronic HCV infection.

Doyle EH, Rahman A, Aloman C, Klepper AL, El-Shamy A, Eng F, Rocha C, Kim S, Haydel B, Florman SS, Fiel MI, Schiano T, Branch AD. Doyle EH, et al. Among authors: klepper al. PLoS Pathog. 2019 Jul 29;15(7):e1007935. doi: 10.1371/journal.ppat.1007935. eCollection 2019 Jul. PLoS Pathog. 2019. PMID: 31356648 Free PMC article.

5

A single N¹-methyladenosine on the large ribosomal subunit rRNA impacts locally its structure and the translation of key metabolic enzymes.

Sharma S, Hartmann JD, Watzinger P, Klepper A, Peifer C, Kötter P, Lafontaine DLJ, Entian KD. Sharma S, et al. Among authors: klepper a. Sci Rep. 2018 Aug 9;8(1):11904. doi: 10.1038/s41598-018-30383-z. Sci Rep. 2018. PMID: 30093689 Free PMC article.

6

Newly discovered hepatitis C virus minicores circulate in human blood.

Eng FJ, El-Shamy A, Doyle EH, Klepper A, Muerhoff AS, Branch AD. Eng FJ, et al. Among authors: klepper a. Hepatol Commun. 2017 Nov 12;2(1):21-28. doi: 10.1002/hep4.1125. eCollection 2018 Jan. Hepatol Commun. 2017. PMID: 29404509 Free PMC article.

7

Hepatitis C virus double-stranded RNA is the predominant form in human liver and in interferon-treated cells.

Klepper A, Eng FJ, Doyle EH, El-Shamy A, Rahman AH, Fiel MI, Avino GC, Lee M, Ye F, Roayaie S, Bansal MB, MacDonald MR, Schiano TD, Branch AD. Klepper A, et al. Hepatology. 2017 Aug;66(2):357-370. doi: 10.1002/hep.28846. Epub 2016 Nov 10. Hepatology. 2017. PMID: 27642141 Free PMC article.

8

A cell culture system for distinguishing hepatitis C viruses with and without liver cancer-related mutations in the viral core gene.

El-Shamy A, Eng FJ, Doyle EH, Klepper AL, Sun X, Sangiovanni A, Iavarone M, Colombo M, Schwartz RE, Hoshida Y, Branch AD. El-Shamy A, et al. Among authors: klepper al. J Hepatol. 2015 Dec;63(6):1323-33. doi: 10.1016/j.jhep.2015.07.024. Epub 2015 Jul 26. J Hepatol. 2015. PMID: 26220749 Free PMC article.

9

Macrophages and the Viral Dissemination Super Highway.

Klepper A, Branch AD. Klepper A, et al. EC Microbiol. 2015;2(3):328-336. EC Microbiol. 2015. PMID: 26949751 Free PMC article.

10

High mobility group box-1 (HMGB1) participates in the pathogenesis of alcoholic liver disease (ALD).

Ge X, Antoine DJ, Lu Y, Arriazu E, Leung TM, Klepper AL, Branch AD, Fiel MI, Nieto N. Ge X, et al. Among authors: klepper al. J Biol Chem. 2014 Aug 15;289(33):22672-22691. doi: 10.1074/jbc.M114.552141. Epub 2014 Jun 13. J Biol Chem. 2014. PMID: 24928512 Free PMC article.

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