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Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance.
Zhan W, Li D, Subramanyaswamy SB, Liu YJ, Yang C, Zhang H, Harris JC, Wang R, Zhu S, Rocha H, Sherman J, Qin J, Herring M, Simwela NV, Waters AP, Sukenick G, Cui L, Rodriguez A, Deng H, Nathan CF, Kirkman LA, Lin G. Zhan W, et al. Cell Chem Biol. 2023 May 18;30(5):457-469.e11. doi: 10.1016/j.chembiol.2023.04.006. Epub 2023 May 5. Cell Chem Biol. 2023. PMID: 37148884 Free PMC article.
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi.
Bosch-Navarrete C, Pérez-Moreno G, Annang F, Diaz-Gonzalez R, García-Hernández R, Rocha H, Gamarro F, Cordón-Obras C, Navarro M, Rodriguez A, Genilloud O, Reyes F, Vicente F, Ruiz-Pérez LM, González-Pacanowska D. Bosch-Navarrete C, et al. PLoS Negl Trop Dis. 2023 Sep 15;17(9):e0011592. doi: 10.1371/journal.pntd.0011592. eCollection 2023 Sep. PLoS Negl Trop Dis. 2023. PMID: 37713416 Free PMC article.
Exploring approaches for predictive cancer patient digital twins: Opportunities for collaboration and innovation.
Stahlberg EA, Abdel-Rahman M, Aguilar B, Asadpoure A, Beckman RA, Borkon LL, Bryan JN, Cebulla CM, Chang YH, Chatterjee A, Deng J, Dolatshahi S, Gevaert O, Greenspan EJ, Hao W, Hernandez-Boussard T, Jackson PR, Kuijjer M, Lee A, Macklin P, Madhavan S, McCoy MD, Mohammad Mirzaei N, Razzaghi T, Rocha HL, Shahriyari L, Shmulevich I, Stover DG, Sun Y, Syeda-Mahmood T, Wang J, Wang Q, Zervantonakis I. Stahlberg EA, et al. Among authors: rocha hl. Front Digit Health. 2022 Oct 6;4:1007784. doi: 10.3389/fdgth.2022.1007784. eCollection 2022. Front Digit Health. 2022. PMID: 36274654 Free PMC article.
CHOLANGIOSCOPY IN A POST-COVID-19 CHOLANGIOPATHY PATIENT.
Franzini TAP, Guedes MMF, Rocha HLOG, Fleury CA, Bestetti AM, Moura EGH. Franzini TAP, et al. Among authors: rocha hlog. Arq Gastroenterol. 2022 Apr-Jun;59(2):321-323. doi: 10.1590/S0004-2803.202202000-58. Arq Gastroenterol. 2022. PMID: 35830050 Free article. No abstract available.
A HYBRID THREE-SCALE MODEL OF TUMOR GROWTH.
Rocha HL, Almeida RC, Lima EABF, Resende ACM, Oden JT, Yankeelov TE. Rocha HL, et al. Math Models Methods Appl Sci. 2018 Jan;28(1):61-93. doi: 10.1142/S0218202518500021. Epub 2017 Nov 24. Math Models Methods Appl Sci. 2018. PMID: 29353950 Free PMC article.
15 results