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Anti-myeloma efficacy of CAR-iNKT is enhanced with a long-acting IL-7, rhIL-7-hyFc.
O'Neal J, Cooper ML, Ritchey JK, Gladney S, Niswonger J, González LS, Street E, Haas GJ, Carter A, Amayta PN, Gao F, Lee BH, Choi D, Berrien-Elliott M, Zhou A, Fehniger TA, Rettig MP, DiPersio JF. O'Neal J, et al. Among authors: gladney s. Blood Adv. 2023 Oct 24;7(20):6009-6022. doi: 10.1182/bloodadvances.2023010032. Blood Adv. 2023. PMID: 37399471 Free PMC article.
CS1 CAR-T targeting the distal domain of CS1 (SLAMF7) shows efficacy in high tumor burden myeloma model despite fratricide of CD8+CS1 expressing CAR-T cells.
O'Neal J, Ritchey JK, Cooper ML, Niswonger J, Sofía González L, Street E, Rettig MP, Gladney SW, Gehrs L, Abboud R, Prior JL, Haas GJ, Jayasinghe RG, Ding L, Ghobadi A, Vij R, DiPersio JF. O'Neal J, et al. Among authors: gladney sw. Leukemia. 2022 Jun;36(6):1625-1634. doi: 10.1038/s41375-022-01559-4. Epub 2022 Apr 14. Leukemia. 2022. PMID: 35422095 Free PMC article.
Managing chronic myeloid leukemia: a coordinated team care perspective.
Holloway S, Lord K, Bethelmie-Bryan B, Shepard MW, Neely J, McLemore M, Reddy SK, Montero A, Jonas WS, Gladney SP, Khanwani SL, Reddy SC, Lahiry AK, Heffner LT, Winton E, Arellano M, Khoury HJ. Holloway S, et al. Among authors: gladney sp. Clin Lymphoma Myeloma Leuk. 2012 Apr;12(2):88-93. doi: 10.1016/j.clml.2011.10.004. Epub 2011 Dec 8. Clin Lymphoma Myeloma Leuk. 2012. PMID: 22154234 Review.