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Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis.
Medina-Gomez C, Mullin BH, Chesi A, Prijatelj V, Kemp JP, Shochat-Carvalho C, Trajanoska K, Wang C, Joro R, Evans TE, Schraut KE, Li-Gao R, Ahluwalia TS, Zillikens MC, Zhu K, Mook-Kanamori DO, Evans DS, Nethander M, Knol MJ, Thorleifsson G, Prokic I, Zemel B, Broer L, McGuigan FE, van Schoor NM, Reppe S, Pawlak MA, Ralston SH, van der Velde N, Lorentzon M, Stefansson K, Adams HHH, Wilson SG, Ikram MA, Walsh JP, Lakka TA, Gautvik KM, Wilson JF, Orwoll ES, van Duijn CM, Bønnelykke K, Uitterlinden AG, Styrkársdóttir U, Akesson KE, Spector TD, Tobias JH, Ohlsson C, Felix JF, Bisgaard H, Grant SFA, Richards JB, Evans DM, van der Eerden B, van de Peppel J, Ackert-Bicknell C, Karasik D, Kague E, Rivadeneira F. Medina-Gomez C, et al. Among authors: van duijn cm, van schoor nm, van de peppel j, van der velde n, van der eerden b. Commun Biol. 2023 Jul 4;6(1):691. doi: 10.1038/s42003-023-04869-0. Commun Biol. 2023. PMID: 37402774 Free PMC article.
The epithelial Ca2+ channel TRPV5 is essential for proper osteoclastic bone resorption.
van der Eerden BC, Hoenderop JG, de Vries TJ, Schoenmaker T, Buurman CJ, Uitterlinden AG, Pols HA, Bindels RJ, van Leeuwen JP. van der Eerden BC, et al. Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17507-12. doi: 10.1073/pnas.0505789102. Epub 2005 Nov 16. Proc Natl Acad Sci U S A. 2005. PMID: 16291808 Free PMC article.
The T-13910C polymorphism in the lactase phlorizin hydrolase gene is associated with differences in serum calcium levels and calcium intake.
Koek WN, van Meurs JB, van der Eerden BC, Rivadeneira F, Zillikens MC, Hofman A, Obermayer-Pietsch B, Lips P, Pols HA, Uitterlinden AG, van Leeuwen JP. Koek WN, et al. Among authors: van leeuwen jp, van meurs jb, van der eerden bc. J Bone Miner Res. 2010 Sep;25(9):1980-7. doi: 10.1002/jbmr.83. J Bone Miner Res. 2010. PMID: 20225268 Free article.
Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment.
Kemp JP, Medina-Gomez C, Estrada K, St Pourcain B, Heppe DH, Warrington NM, Oei L, Ring SM, Kruithof CJ, Timpson NJ, Wolber LE, Reppe S, Gautvik K, Grundberg E, Ge B, van der Eerden B, van de Peppel J, Hibbs MA, Ackert-Bicknell CL, Choi K, Koller DL, Econs MJ, Williams FM, Foroud T, Zillikens MC, Ohlsson C, Hofman A, Uitterlinden AG, Davey Smith G, Jaddoe VW, Tobias JH, Rivadeneira F, Evans DM. Kemp JP, et al. Among authors: van de peppel j, van der eerden b. PLoS Genet. 2014 Jun 19;10(6):e1004423. doi: 10.1371/journal.pgen.1004423. eCollection 2014 Jun. PLoS Genet. 2014. PMID: 24945404 Free PMC article.
Serum Phosphate Is Associated With Fracture Risk: The Rotterdam Study and MrOS.
Campos-Obando N, Koek WNH, Hooker ER, van der Eerden BC, Pols HA, Hofman A, van Leeuwen JP, Uitterlinden AG, Nielson CM, Zillikens MC. Campos-Obando N, et al. J Bone Miner Res. 2017 Jun;32(6):1182-1193. doi: 10.1002/jbmr.3094. Epub 2017 Mar 27. J Bone Miner Res. 2017. PMID: 28177140 Free PMC article.
Hydroxychloroquine affects bone resorption both in vitro and in vivo.
Both T, Zillikens MC, Schreuders-Koedam M, Vis M, Lam WK, Weel AEAM, van Leeuwen JPTM, van Hagen PM, van der Eerden BCJ, van Daele PLA. Both T, et al. J Cell Physiol. 2018 Feb;233(2):1424-1433. doi: 10.1002/jcp.26028. Epub 2017 Aug 3. J Cell Physiol. 2018. PMID: 28556961
129 results