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Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells.
Mognol GP, Spreafico R, Wong V, Scott-Browne JP, Togher S, Hoffmann A, Hogan PG, Rao A, Trifari S. Mognol GP, et al. Proc Natl Acad Sci U S A. 2017 Mar 28;114(13):E2776-E2785. doi: 10.1073/pnas.1620498114. Epub 2017 Mar 10. Proc Natl Acad Sci U S A. 2017. PMID: 28283662 Free PMC article.
TET proteins in natural and induced differentiation.
Scott-Browne JP, Lio CJ, Rao A. Scott-Browne JP, et al. Curr Opin Genet Dev. 2017 Oct;46:202-208. doi: 10.1016/j.gde.2017.07.011. Epub 2017 Sep 6. Curr Opin Genet Dev. 2017. PMID: 28888139 Free PMC article. Review.
NR4A transcription factors limit CAR T cell function in solid tumours.
Chen J, López-Moyado IF, Seo H, Lio CJ, Hempleman LJ, Sekiya T, Yoshimura A, Scott-Browne JP, Rao A. Chen J, et al. Nature. 2019 Mar;567(7749):530-534. doi: 10.1038/s41586-019-0985-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814732 Free PMC article.
An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T. Bajaj J, et al. Nat Cancer. 2020 Apr;1(4):410-422. doi: 10.1038/s43018-020-0054-2. Epub 2020 Apr 20. Nat Cancer. 2020. PMID: 34109316 Free PMC article.
TCR signal strength controls thymic differentiation of iNKT cell subsets.
Tuttle KD, Krovi SH, Zhang J, Bedel R, Harmacek L, Peterson LK, Dragone LL, Lefferts A, Halluszczak C, Riemondy K, Hesselberth JR, Rao A, O'Connor BP, Marrack P, Scott-Browne J, Gapin L. Tuttle KD, et al. Nat Commun. 2018 Jul 9;9(1):2650. doi: 10.1038/s41467-018-05026-6. Nat Commun. 2018. PMID: 29985393 Free PMC article.
43 results