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Tropomyosin1 isoforms underlie epithelial to mesenchymal plasticity, metastatic dissemination, and resistance to chemotherapy in high-grade serous ovarian cancer.
Xu T, Verhagen MP, Teeuwssen M, Sun W, Joosten R, Sacchetti A, Ewing-Graham PC, Jansen MPHM, Boere IA, Bryce NS, Zeng J, Treutlein HR, Hook J, Hardeman EC, Gunning PW, Fodde R. Xu T, et al. Among authors: hardeman ec. Cell Death Differ. 2024 Mar;31(3):360-377. doi: 10.1038/s41418-024-01267-9. Epub 2024 Feb 16. Cell Death Differ. 2024. PMID: 38365970 Free PMC article.
Spatial and Temporal Coordination of Force-generating Actin-based Modules Drives Membrane Remodeling In Vivo.
Heydecker M, Shitara A, Chen D, Tran D, Masedunskas A, Tora M, Ebrahim S, Appaduray MA, Galeano Niño JL, Bhardwaj A, Narayan K, Hardeman EC, Gunning PW, Weigert R. Heydecker M, et al. Among authors: hardeman ec. bioRxiv [Preprint]. 2023 Dec 5:2023.12.04.569944. doi: 10.1101/2023.12.04.569944. bioRxiv. 2023. PMID: 38168275 Free PMC article. Preprint.
Highly efficient platelet generation in lung vasculature reproduced by microfluidics.
Zhao X, Alibhai D, Walsh TG, Tarassova N, Englert M, Birol SZ, Li Y, Williams CM, Neal CR, Burkard P, Cross SJ, Aitken EW, Waller AK, Beltrán JB, Gunning PW, Hardeman EC, Agbani EO, Nieswandt B, Hers I, Ghevaert C, Poole AW. Zhao X, et al. Among authors: hardeman ec. Nat Commun. 2023 Jul 7;14(1):4026. doi: 10.1038/s41467-023-39598-9. Nat Commun. 2023. PMID: 37419900 Free PMC article.
Different Mouse Models of Nemaline Myopathy Harboring Acta1 Mutations Display Differing Abnormalities Related to Mitochondrial Biology.
Tinklenberg JA, Slick RA, Sutton J, Zhang L, Meng H, Beatka MJ, Vanden Avond M, Prom MJ, Ott E, Montanaro F, Heisner J, Toro R, Hardeman EC, Geurts AM, Stowe DF, Hill RB, Lawlor MW. Tinklenberg JA, et al. Among authors: hardeman ec. Am J Pathol. 2023 Oct;193(10):1548-1567. doi: 10.1016/j.ajpath.2023.06.008. Epub 2023 Jul 5. Am J Pathol. 2023. PMID: 37419385
Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents.
Xu X, Wang Y, Bryce NS, Tang K, Meagher NS, Kang EY, Kelemen LE, Köbel M, Ramus SJ, Friedlander M, Ford CE, Hardeman EC, Gunning PW. Xu X, et al. Among authors: hardeman ec. Br J Cancer. 2021 Jul;125(2):265-276. doi: 10.1038/s41416-021-01420-y. Epub 2021 May 12. Br J Cancer. 2021. PMID: 33981016 Free PMC article.
A robust method for particulate detection of a genetic tag for 3D electron microscopy.
Rae J, Ferguson C, Ariotti N, Webb RI, Cheng HH, Mead JL, Riches JD, Hunter DJ, Martel N, Baltos J, Christopoulos A, Bryce NS, Cagigas ML, Fonseka S, Sayre ME, Hardeman EC, Gunning PW, Gambin Y, Hall TE, Parton RG. Rae J, et al. Among authors: hardeman ec. Elife. 2021 Apr 27;10:e64630. doi: 10.7554/eLife.64630. Elife. 2021. PMID: 33904409 Free PMC article.
120 results