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Structure and functionality of a multimeric human COQ7:COQ9 complex.
Manicki M, Aydin H, Abriata LA, Overmyer KA, Guerra RM, Coon JJ, Dal Peraro M, Frost A, Pagliarini DJ. Manicki M, et al. Mol Cell. 2022 Nov 17;82(22):4307-4323.e10. doi: 10.1016/j.molcel.2022.10.003. Epub 2022 Oct 27. Mol Cell. 2022. PMID: 36306796 Free PMC article.
Coenzyme Q biochemistry and biosynthesis.
Guerra RM, Pagliarini DJ. Guerra RM, et al. Trends Biochem Sci. 2023 May;48(5):463-476. doi: 10.1016/j.tibs.2022.12.006. Epub 2023 Jan 24. Trends Biochem Sci. 2023. PMID: 36702698 Free PMC article. Review.
Hem25p is a mitochondrial IPP transporter.
Tai J, Guerra RM, Rogers SW, Fang Z, Muehlbauer LK, Shishkova E, Overmyer KA, Coon JJ, Pagliarini DJ. Tai J, et al. bioRxiv [Preprint]. 2023 Mar 14:2023.03.14.532620. doi: 10.1101/2023.03.14.532620. bioRxiv. 2023. PMID: 36993473 Free PMC article. Updated. Preprint.
Hem25p is required for mitochondrial IPP transport in fungi.
Tai J, Guerra RM, Rogers SW, Fang Z, Muehlbauer LK, Shishkova E, Overmyer KA, Coon JJ, Pagliarini DJ. Tai J, et al. Nat Cell Biol. 2023 Nov;25(11):1616-1624. doi: 10.1038/s41556-023-01250-5. Epub 2023 Oct 9. Nat Cell Biol. 2023. PMID: 37813972 Free PMC article.
Reducing mitochondrial mysteries.
Guerra RM, Pagliarini DJ. Guerra RM, et al. Nat Chem Biol. 2024 Feb;20(2):132-133. doi: 10.1038/s41589-023-01435-x. Nat Chem Biol. 2024. PMID: 37884804 No abstract available.
COQ4 is required for the oxidative decarboxylation of the C1 carbon of Coenzyme Q in eukaryotic cells.
Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, García-Corzo L, Sánchez-Cuesta A, Navas P, Brea-Calvo G, Trevisson E, Wendisch VF, Pagliarini DJ, Salviati L, Pierrel F. Pelosi L, et al. bioRxiv [Preprint]. 2023 Nov 13:2023.11.13.566839. doi: 10.1101/2023.11.13.566839. bioRxiv. 2023. PMID: 38014142 Free PMC article. Updated. Preprint.
COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells.
Pelosi L, Morbiato L, Burgardt A, Tonello F, Bartlett AK, Guerra RM, Ferizhendi KK, Desbats MA, Rascalou B, Marchi M, Vázquez-Fonseca L, Agosto C, Zanotti G, Roger-Margueritat M, Alcázar-Fabra M, García-Corzo L, Sánchez-Cuesta A, Navas P, Brea-Calvo G, Trevisson E, Wendisch VF, Pagliarini DJ, Salviati L, Pierrel F. Pelosi L, et al. Mol Cell. 2024 Mar 7;84(5):981-989.e7. doi: 10.1016/j.molcel.2024.01.003. Epub 2024 Jan 30. Mol Cell. 2024. PMID: 38295803
BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III.
Chen B, Lynn-Nguyen TM, Jadhav P, Halligan BS, Rossiter NJ, Guerra RM, Koshkin S, Koo I, Morlacchi P, Hanna DA, Lin J, Banerjee R, Pagliarini DJ, Patterson AD, Mosalaganti S, Sexton JZ, Calì T, Lyssiotis CA, Shah YM. Chen B, et al. Among authors: guerra rm. bioRxiv [Preprint]. 2024 Feb 4:2024.02.02.578646. doi: 10.1101/2024.02.02.578646. bioRxiv. 2024. PMID: 38352460 Free PMC article. Preprint.
836 results