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Page 1
ALK peptide vaccination restores the immunogenicity of ALK-rearranged non-small cell lung cancer.
Mota I, Patrucco E, Mastini C, Mahadevan NR, Thai TC, Bergaggio E, Cheong TC, Leonardi G, Karaca-Atabay E, Campisi M, Poggio T, Menotti M, Ambrogio C, Longo DL, Klaeger S, Keshishian H, Sztupinszki ZM, Szallasi Z, Keskin DB, Duke-Cohan JS, Reinhold B, Carr SA, Wu CJ, Moynihan KD, Irvine DJ, Barbie DA, Reinherz EL, Voena C, Awad MM, Blasco RB, Chiarle R. Mota I, et al. Among authors: klaeger s. Nat Cancer. 2023 Jul;4(7):1016-1035. doi: 10.1038/s43018-023-00591-2. Epub 2023 Jul 10. Nat Cancer. 2023. PMID: 37430060
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma.
Oliveira G, Stromhaug K, Klaeger S, Kula T, Frederick DT, Le PM, Forman J, Huang T, Li S, Zhang W, Xu Q, Cieri N, Clauser KR, Shukla SA, Neuberg D, Justesen S, MacBeath G, Carr SA, Fritsch EF, Hacohen N, Sade-Feldman M, Livak KJ, Boland GM, Ott PA, Keskin DB, Wu CJ. Oliveira G, et al. Among authors: klaeger s. Nature. 2021 Aug;596(7870):119-125. doi: 10.1038/s41586-021-03704-y. Epub 2021 Jul 21. Nature. 2021. PMID: 34290406 Free PMC article.
A large peptidome dataset improves HLA class I epitope prediction across most of the human population.
Sarkizova S, Klaeger S, Le PM, Li LW, Oliveira G, Keshishian H, Hartigan CR, Zhang W, Braun DA, Ligon KL, Bachireddy P, Zervantonakis IK, Rosenbluth JM, Ouspenskaia T, Law T, Justesen S, Stevens J, Lane WJ, Eisenhaure T, Lan Zhang G, Clauser KR, Hacohen N, Carr SA, Wu CJ, Keskin DB. Sarkizova S, et al. Among authors: klaeger s. Nat Biotechnol. 2020 Feb;38(2):199-209. doi: 10.1038/s41587-019-0322-9. Epub 2019 Dec 16. Nat Biotechnol. 2020. PMID: 31844290 Free PMC article.
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer.
Ouspenskaia T, Law T, Clauser KR, Klaeger S, Sarkizova S, Aguet F, Li B, Christian E, Knisbacher BA, Le PM, Hartigan CR, Keshishian H, Apffel A, Oliveira G, Zhang W, Chen S, Chow YT, Ji Z, Jungreis I, Shukla SA, Justesen S, Bachireddy P, Kellis M, Getz G, Hacohen N, Keskin DB, Carr SA, Wu CJ, Regev A. Ouspenskaia T, et al. Among authors: klaeger s. Nat Biotechnol. 2022 Feb;40(2):209-217. doi: 10.1038/s41587-021-01021-3. Epub 2021 Oct 18. Nat Biotechnol. 2022. PMID: 34663921 Free PMC article.
Landscape of helper and regulatory antitumour CD4+ T cells in melanoma.
Oliveira G, Stromhaug K, Cieri N, Iorgulescu JB, Klaeger S, Wolff JO, Rachimi S, Chea V, Krause K, Freeman SS, Zhang W, Li S, Braun DA, Neuberg D, Carr SA, Livak KJ, Frederick DT, Fritsch EF, Wind-Rotolo M, Hacohen N, Sade-Feldman M, Yoon CH, Keskin DB, Ott PA, Rodig SJ, Boland GM, Wu CJ. Oliveira G, et al. Among authors: klaeger s. Nature. 2022 May;605(7910):532-538. doi: 10.1038/s41586-022-04682-5. Epub 2022 May 4. Nature. 2022. PMID: 35508657 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35555650
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity.
Griffin GK, Wu J, Iracheta-Vellve A, Patti JC, Hsu J, Davis T, Dele-Oni D, Du PP, Halawi AG, Ishizuka JJ, Kim SY, Klaeger S, Knudsen NH, Miller BC, Nguyen TH, Olander KE, Papanastasiou M, Rachimi S, Robitschek EJ, Schneider EM, Yeary MD, Zimmer MD, Jaffe JD, Carr SA, Doench JG, Haining WN, Yates KB, Manguso RT, Bernstein BE. Griffin GK, et al. Among authors: klaeger s. Nature. 2021 Jul;595(7866):309-314. doi: 10.1038/s41586-021-03520-4. Epub 2021 May 5. Nature. 2021. PMID: 33953401 Free PMC article.
Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.
Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Ananthapadmanabhan V, Frost TC, Stevens JD, Wong AY, Iorgulescu JB, Tarren AY, Chea VA, Carulli IP, Lemvigh CK, Pedersen CB, Gartin AK, Sarkizova S, Wright KT, Li LW, Nomburg J, Li S, Huang T, Liu X, Pomerance L, Doherty LM, Apffel AM, Wallace LJ, Rachimi S, Felt KD, Wolff JO, Witten E, Zhang W, Neuberg D, Lane WJ, Zhang G, Olsen LR, Thakuria M, Rodig SJ, Clauser KR, Starrett GJ, Doench JG, Buhrlage SJ, Carr SA, DeCaprio JA, Wu CJ, Keskin DB. Lee PC, et al. Among authors: klaeger s. J Clin Invest. 2022 Jul 1;132(13):e151666. doi: 10.1172/JCI151666. J Clin Invest. 2022. PMID: 35775490 Free PMC article.
42 results