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Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
Riemenschneider H, Simonetti F, Sheth U, Katona E, Roth S, Hutten S, Farny D, Michaelsen M, Nuscher B, Schmidt MK, Flatley A, Schepers A, Gruijs da Silva LA, Zhou Q, Klopstock T, Liesz A, Arzberger T, Herms J, Feederle R, Gendron TF, Dormann D, Edbauer D. Riemenschneider H, et al. Among authors: gruijs da silva la. Acta Neuropathol Commun. 2023 Jul 11;11(1):112. doi: 10.1186/s40478-023-01592-z. Acta Neuropathol Commun. 2023. PMID: 37434215 Free PMC article.
Creating overview and summary figures.
Critcher M, Gruijs da Silva LA, Dormann D, Campbell ZT, Le TK, Rocchi P, Sorgenfrei M. Critcher M, et al. Among authors: gruijs da silva la. Trends Biochem Sci. 2023 Feb;48(2):97-99. doi: 10.1016/j.tibs.2022.09.009. Trends Biochem Sci. 2023. PMID: 36669467 No abstract available.