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Pan-Cancer Pharmacogenomic Analysis of Patient-Derived Tumor Cells Using Clinically Relevant Drug Exposures.
Chang SH, Ice RJ, Chen M, Sidorov M, Woo RWL, Rodriguez-Brotons A, Jian D, Kim HK, Kim A, Stone DE, Nazarian A, Oh A, Tranah GJ, Nosrati M, de Semir D, Dar AA, Desprez PY, Kashani-Sabet M, Soroceanu L, McAllister SD. Chang SH, et al. Among authors: soroceanu l. Mol Cancer Ther. 2023 Sep 5;22(9):1100-1111. doi: 10.1158/1535-7163.MCT-22-0486. Mol Cancer Ther. 2023. PMID: 37440705
Pitfalls and Rewards of Setting Up a Liquid Biopsy Approach for the Detection of Driver Mutations in Circulating Tumor DNAs: Our Institutional Experience.
Chen M, Jian D, Sidorov M, Woo RWL, Kim A, Stone DE, Nazarian A, Nosrati M, Ice RJ, de Semir D, Dar AA, Luštrik R, Kokošar J, Ausec L, Rowbotham MC, Tranah GJ, Kashani-Sabet M, Soroceanu L, McAllister SD, Desprez PY. Chen M, et al. Among authors: soroceanu l. J Pers Med. 2022 Nov 4;12(11):1845. doi: 10.3390/jpm12111845. J Pers Med. 2022. PMID: 36579573 Free PMC article.
The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations.
Balasooriya ER, Wu Q, Ellis H, Zhen Y, Norden BL, Corcoran RB, Mohan A, Martin E, Franovic A, Tyhonas J, Lardy M, Grandinetti KB, Pelham R, Soroceanu L, Silveira VS, Bardeesy N. Balasooriya ER, et al. Among authors: soroceanu l. Clin Cancer Res. 2024 May 15;30(10):2181-2192. doi: 10.1158/1078-0432.CCR-23-3588. Clin Cancer Res. 2024. PMID: 38437671
Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations.
Tyhonas JS, Arnold LD, Cox JM, Franovic A, Gardiner E, Grandinetti K, Kania R, Kanouni T, Lardy M, Li C, Martin ES, Miller N, Mohan A, Murphy EA, Perez M, Soroceanu L, Timple N, Uryu S, Womble S, Kaldor SW. Tyhonas JS, et al. Among authors: soroceanu l. J Med Chem. 2024 Feb 8;67(3):1734-1746. doi: 10.1021/acs.jmedchem.3c01819. Epub 2024 Jan 24. J Med Chem. 2024. PMID: 38267212
Functional genomic analysis of adult and pediatric brain tumor isolates.
Hoellerbauer P, Biery MC, Arora S, Rao Y, Girard EJ, Mitchell K, Dighe P, Kufeld M, Kuppers DA, Herman JA, Holland EC, Soroceanu L, Vitanza NA, Olson JM, Pritchard JR, Paddison PJ. Hoellerbauer P, et al. Among authors: soroceanu l. bioRxiv [Preprint]. 2023 Jan 6:2023.01.05.522885. doi: 10.1101/2023.01.05.522885. bioRxiv. 2023. PMID: 36711964 Free PMC article. Preprint.
Bromodomain inhibition overcomes treatment resistance in distinct molecular subtypes of melanoma.
Dar AA, Bezrookove V, Nosrati M, Ice R, Patino JM, Vaquero EM, Parrett B, Leong SP, Kim KB, Debs RJ, Soroceanu L, Miller JR 3rd, Desprez PY, Cleaver JE, Salomonis N, McAllister S, Kashani-Sabet M. Dar AA, et al. Among authors: soroceanu l. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2206824119. doi: 10.1073/pnas.2206824119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969744 Free PMC article.
53 results