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A mucin degrader for cancer therapy.
Beatson R, Burchell JM. Beatson R, et al. Among authors: burchell jm. Nat Biotechnol. 2024 Apr;42(4):572-573. doi: 10.1038/s41587-023-01984-5. Nat Biotechnol. 2024. PMID: 37813982 No abstract available.
LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer.
Anstee JE, Feehan KT, Opzoomer JW, Dean I, Muller HP, Bahri M, Cheung TS, Liakath-Ali K, Liu Z, Choy D, Caron J, Sosnowska D, Beatson R, Muliaditan T, An Z, Gillett CE, Lan G, Zou X, Watt FM, Ng T, Burchell JM, Kordasti S, Withers DR, Lawrence T, Arnold JN. Anstee JE, et al. Among authors: burchell jm. Dev Cell. 2023 Sep 11;58(17):1548-1561.e10. doi: 10.1016/j.devcel.2023.06.006. Epub 2023 Jul 12. Dev Cell. 2023. PMID: 37442140 Free article.
Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype.
Beatson R, Graham R, Grundland Freile F, Cozzetto D, Kannambath S, Pfeifer E, Woodman N, Owen J, Nuamah R, Mandel U, Pinder S, Gillett C, Noll T, Bouybayoune I, Taylor-Papadimitriou J, Burchell JM. Beatson R, et al. Among authors: burchell jm. Commun Biol. 2020 Nov 4;3(1):644. doi: 10.1038/s42003-020-01359-5. Commun Biol. 2020. PMID: 33149188 Free PMC article.
O-linked mucin-type glycosylation in breast cancer.
Burchell JM, Beatson R, Graham R, Taylor-Papadimitriou J, Tajadura-Ortega V. Burchell JM, et al. Biochem Soc Trans. 2018 Aug 20;46(4):779-788. doi: 10.1042/BST20170483. Epub 2018 Jun 14. Biochem Soc Trans. 2018. PMID: 29903935 Free PMC article. Review.
Latest developments in MUC1 immunotherapy.
Taylor-Papadimitriou J, Burchell JM, Graham R, Beatson R. Taylor-Papadimitriou J, et al. Among authors: burchell jm. Biochem Soc Trans. 2018 Jun 19;46(3):659-668. doi: 10.1042/BST20170400. Epub 2018 May 21. Biochem Soc Trans. 2018. PMID: 29784646 Free PMC article. Review.
Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer.
Muliaditan T, Opzoomer JW, Caron J, Okesola M, Kosti P, Lall S, Van Hemelrijck M, Dazzi F, Tutt A, Grigoriadis A, Gillett CE, Madden SF, Burchell JM, Kordasti S, Diebold SS, Spicer JF, Arnold JN. Muliaditan T, et al. Among authors: burchell jm. Clin Cancer Res. 2018 Apr 1;24(7):1617-1628. doi: 10.1158/1078-0432.CCR-17-2587. Epub 2018 Jan 16. Clin Cancer Res. 2018. PMID: 29339440 Free PMC article.
56 results