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Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils.
Tayeb-Fligelman E, Bowler JT, Tai CE, Sawaya MR, Jiang YX, Garcia G Jr, Griner SL, Cheng X, Salwinski L, Lutter L, Seidler PM, Lu J, Rosenberg GM, Hou K, Abskharon R, Pan H, Zee CT, Boyer DR, Li Y, Anderson DH, Murray KA, Falcon G, Cascio D, Saelices L, Damoiseaux R, Arumugaswami V, Guo F, Eisenberg DS. Tayeb-Fligelman E, et al. Among authors: rosenberg gm. Nat Commun. 2023 Apr 25;14(1):2379. doi: 10.1038/s41467-023-37865-3. Nat Commun. 2023. PMID: 37185252 Free PMC article.
A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism.
Seldin MM, Koplev S, Rajbhandari P, Vergnes L, Rosenberg GM, Meng Y, Pan C, Phuong TMN, Gharakhanian R, Che N, Mäkinen S, Shih DM, Civelek M, Parks BW, Kim ED, Norheim F, Chella Krishnan K, Hasin-Brumshtein Y, Mehrabian M, Laakso M, Drevon CA, Koistinen HA, Tontonoz P, Reue K, Cantor RM, Björkegren JLM, Lusis AJ. Seldin MM, et al. Cell Metab. 2018 May 1;27(5):1138-1155.e6. doi: 10.1016/j.cmet.2018.03.015. Cell Metab. 2018. PMID: 29719227 Free PMC article.
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA, Hu CJ, Pan H, Lu J, Abskharon R, Bowler JT, Rosenberg GM, Williams CK, Elezi G, Balbirnie M, Faull KF, Vinters HV, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: rosenberg gm. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2217835120. doi: 10.1073/pnas.2217835120. Epub 2023 Feb 9. Proc Natl Acad Sci U S A. 2023. PMID: 36757890 Free PMC article.
Structure-based inhibitors halt prion-like seeding by Alzheimer's disease-and tauopathy-derived brain tissue samples.
Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS. Seidler PM, et al. Among authors: rosenberg g. J Biol Chem. 2019 Nov 1;294(44):16451-16464. doi: 10.1074/jbc.RA119.009688. Epub 2019 Sep 19. J Biol Chem. 2019. PMID: 31537646 Free PMC article.
Development of the PSU Child Pump.
Scheib C, Newswanger R, Cysyk J, Bohnenberger K, Lukic B, Xu L, Yeager E, Bletcher K, Leibich P, Jackson Q, Flory H, Tillinger M, Weiss W, Rosenberg G, Jhun CS. Scheib C, et al. Among authors: rosenberg g. ASAIO J. 2024 Mar 28. doi: 10.1097/MAT.0000000000002202. Online ahead of print. ASAIO J. 2024. PMID: 38537074
645 results