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Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells.
Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, Hegde S, Gandhi UH, Finch ER, Goodfield L, Quickel MD, Claxton DF, Paulson RF, Prabhu KS. Qian F, et al. Among authors: claxton df. Cell Rep. 2023 Jul 25;42(7):112794. doi: 10.1016/j.celrep.2023.112794. Epub 2023 Jul 18. Cell Rep. 2023. PMID: 37459233 Free PMC article.
Acute myeloid leukemia stratifies as two clinically relevant sphingolipidomic subtypes.
Paudel BB, Tan SF, Fox TE, Ung J, Shaw J, Dunton W, Lee I, Sharma A, Viny AD, Barth BM, Tallman MS, Cabot M, Garrett-Bakelman FE, Levine RL, Kester M, Claxton D, Feith DJ, Janes KA, Loughran TP Jr. Paudel BB, et al. bioRxiv [Preprint]. 2023 Apr 17:2023.04.13.536805. doi: 10.1101/2023.04.13.536805. bioRxiv. 2023. PMID: 37131653 Free PMC article. Updated. Preprint.
Acid Ceramidase Inhibitor LCL-805 Antagonizes Akt Signaling and Promotes Iron-Dependent Cell Death in Acute Myeloid Leukemia.
Ung J, Tan SF, Fox TE, Shaw JJ, Taori M, Horton BJ, Golla U, Sharma A, Szulc ZM, Wang HG, Chalfant CE, Cabot MC, Claxton DF, Loughran TP, Feith DJ. Ung J, et al. Among authors: claxton df. bioRxiv [Preprint]. 2023 Oct 23:2023.10.21.563437. doi: 10.1101/2023.10.21.563437. bioRxiv. 2023. PMID: 37961314 Free PMC article. Updated. Preprint.
Engraftment and Measurable Residual Disease Monitoring after Hematopoietic Stem Cell Transplantation: Comparison of Two Chimerism Test Strategies, Next-Generation Sequencing versus a Combination of Short-Tandem Repeats and Quantitative PCR.
Zhang A, Macecevic S, Thomas D, Allen J, Mandley S, Kawczak P, Jurcago R, Tyler J, Casey H, Bosler D, Sobecks R, Hamilton B, Sauter C, Mineishi S, Claxton D, Shike H. Zhang A, et al. J Mol Diagn. 2024 Apr;26(4):233-244. doi: 10.1016/j.jmoldx.2024.01.007. Epub 2024 Feb 1. J Mol Diagn. 2024. PMID: 38307253
Assessment of chimerism by next generation sequencing: A comparison to STR/qPCR methods.
Brow D, Shike H, Kendrick J, Pettersson L, Mineishi S, Claxton DF, Wirk B, Cioccio J, Greiner RJ, Viswanatha D, Kharfan-Dabaja MA, Li Z, Tyler J, Elrefaei M. Brow D, et al. Among authors: claxton df. Hum Immunol. 2024 Mar 28:110794. doi: 10.1016/j.humimm.2024.110794. Online ahead of print. Hum Immunol. 2024. PMID: 38553384
Simultaneous Inhibition of Ceramide Hydrolysis and Glycosylation Synergizes to Corrupt Mitochondrial Respiration and Signal Caspase Driven Cell Death in Drug-Resistant Acute Myeloid Leukemia.
Fisher-Wellman KH, Kassai M, Hagen JT, Neufer PD, Kester M, Loughran TP Jr, Chalfant CE, Feith DJ, Tan SF, Fox TE, Ung J, Fabrias G, Abad JL, Sharma A, Golla U, Claxton DF, Shaw JJP, Bhowmick D, Cabot MC. Fisher-Wellman KH, et al. Among authors: claxton df. Cancers (Basel). 2023 Mar 21;15(6):1883. doi: 10.3390/cancers15061883. Cancers (Basel). 2023. PMID: 36980769 Free PMC article.
The impact of early PEG-asparaginase discontinuation in young adults with ALL: a post hoc analysis of the CALGB 10403 study.
Aldoss I, Yin J, Wall A, Mrózek K, Liedtke M, Claxton DF, Foster MC, Appelbaum FR, Erba HP, Litzow MR, Tallman MS, Stone RM, Larson RA, Advani AS, Stock W, Luger SM. Aldoss I, et al. Among authors: claxton df. Blood Adv. 2023 Jan 24;7(2):196-204. doi: 10.1182/bloodadvances.2022007791. Blood Adv. 2023. PMID: 36269846 Free PMC article.
97 results