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Activation of GPR44 decreases severity of myeloid leukemia via specific targeting of leukemia initiating stem cells.
Qian F, Nettleford SK, Zhou J, Arner BE, Hall MA, Sharma A, Annageldiyev C, Rossi RM, Tukaramrao DB, Sarkar D, Hegde S, Gandhi UH, Finch ER, Goodfield L, Quickel MD, Claxton DF, Paulson RF, Prabhu KS. Qian F, et al. Among authors: hegde s. Cell Rep. 2023 Jul 25;42(7):112794. doi: 10.1016/j.celrep.2023.112794. Epub 2023 Jul 18. Cell Rep. 2023. PMID: 37459233 Free PMC article.
Selenium suppresses leukemia through the action of endogenous eicosanoids.
Gandhi UH, Kaushal N, Hegde S, Finch ER, Kudva AK, Kennett MJ, Jordan CT, Paulson RF, Prabhu KS. Gandhi UH, et al. Among authors: hegde s. Cancer Res. 2014 Jul 15;74(14):3890-901. doi: 10.1158/0008-5472.CAN-13-3694. Epub 2014 May 28. Cancer Res. 2014. PMID: 24872387 Free PMC article.
SKI-178: A Multitargeted Inhibitor of Sphingosine Kinase and Microtubule Dynamics Demonstrating Therapeutic Efficacy in Acute Myeloid Leukemia Models.
Hengst JA, Dick TE, Sharma A, Doi K, Hegde S, Tan SF, Geffert LM, Fox TE, Sharma AK, Desai D, Amin S, Kester M, Loughran TP, Paulson RF, Claxton DF, Wang HG, Yun JK. Hengst JA, et al. Among authors: hegde s. Cancer Transl Med. 2017 Jul-Aug;3(4):109-121. doi: 10.4103/ctm.ctm_7_17. Epub 2017 Aug 14. Cancer Transl Med. 2017. PMID: 28890935 Free PMC article.
The regulation of erythropoiesis by selenium in mice.
Kaushal N, Hegde S, Lumadue J, Paulson RF, Prabhu KS. Kaushal N, et al. Among authors: hegde s. Antioxid Redox Signal. 2011 Apr 15;14(8):1403-12. doi: 10.1089/ars.2010.3323. Epub 2011 Feb 25. Antioxid Redox Signal. 2011. PMID: 20969477 Free PMC article.
Selenoprotein-dependent up-regulation of hematopoietic prostaglandin D2 synthase in macrophages is mediated through the activation of peroxisome proliferator-activated receptor (PPAR) gamma.
Gandhi UH, Kaushal N, Ravindra KC, Hegde S, Nelson SM, Narayan V, Vunta H, Paulson RF, Prabhu KS. Gandhi UH, et al. Among authors: hegde s. J Biol Chem. 2011 Aug 5;286(31):27471-82. doi: 10.1074/jbc.M111.260547. Epub 2011 Jun 13. J Biol Chem. 2011. PMID: 21669866 Free PMC article.
1,141 results