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Long-range gene regulation in hormone-dependent cancer.
Tettey TT, Rinaldi L, Hager GL. Tettey TT, et al. Nat Rev Cancer. 2023 Oct;23(10):657-672. doi: 10.1038/s41568-023-00603-4. Epub 2023 Aug 3. Nat Rev Cancer. 2023. PMID: 37537310 Review.
SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Nigam N, Bernard B, Sevilla S, Kim S, Dar MS, Tsai D, Robbins Y, Burkitt K, Sievers C, Allen CT, Bennett RL, Tettey TT, Carter B, Rinaldi L, Lingen MW, Sater H, Edmondson EF, Moshiri A, Saeed A, Cheng H, Luo X, Brennan K, Koparde V, Chen C, Das S, Andresson T, Abdelmaksoud A, Murali M, Sakata S, Takeuchi K, Chari R, Nakamura Y, Uppaluri R, Sunwoo JB, Van Waes C, Licht JD, Hager GL, Saloura V. Nigam N, et al. Among authors: tettey tt. Cell Rep. 2023 Jul 25;42(7):112823. doi: 10.1016/j.celrep.2023.112823. Epub 2023 Jul 17. Cell Rep. 2023. PMID: 37463106 Free PMC article.
The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Jiménez-Panizo A, Alegre-Martí A, Tettey TT, Fettweis G, Abella M, Antón R, Johnson TA, Kim S, Schiltz RL, Núñez-Barrios I, Font-Díaz J, Caelles C, Valledor AF, Pérez P, Rojas AM, Fernández-Recio J, Presman DM, Hager GL, Fuentes-Prior P, Estébanez-Perpiñá E. Jiménez-Panizo A, et al. Among authors: tettey tt. Nucleic Acids Res. 2022 Dec 9;50(22):13063-13082. doi: 10.1093/nar/gkac1119. Nucleic Acids Res. 2022. PMID: 36464162 Free PMC article.
BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential.
Miah S, Banks CAS, Ogunbolude Y, Bagu ET, Berg JM, Saraf A, Tettey TT, Hattem G, Dayebgadoh G, Kempf CG, Sardiu M, Napper S, Florens L, Lukong KE, Washburn MP. Miah S, et al. Among authors: tettey tt. Sci Adv. 2019 Oct 23;5(10):eaaw3113. doi: 10.1126/sciadv.aaw3113. eCollection 2019 Oct. Sci Adv. 2019. PMID: 31681835 Free PMC article.
A Role for FACT in RNA Polymerase II Promoter-Proximal Pausing.
Tettey TT, Gao X, Shao W, Li H, Story BA, Chitsazan AD, Glaser RL, Goode ZH, Seidel CW, Conaway RC, Zeitlinger J, Blanchette M, Conaway JW. Tettey TT, et al. Cell Rep. 2019 Jun 25;27(13):3770-3779.e7. doi: 10.1016/j.celrep.2019.05.099. Cell Rep. 2019. PMID: 31242411 Free article.