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Diverse clonal fates emerge upon drug treatment of homogeneous cancer cells.
Goyal Y, Busch GT, Pillai M, Li J, Boe RH, Grody EI, Chelvanambi M, Dardani IP, Emert B, Bodkin N, Braun J, Fingerman D, Kaur A, Jain N, Ravindran PT, Mellis IA, Kiani K, Alicea GM, Fane ME, Ahmed SS, Li H, Chen Y, Chai C, Kaster J, Witt RG, Lazcano R, Ingram DR, Johnson SB, Wani K, Dunagin MC, Lazar AJ, Weeraratna AT, Wargo JA, Herlyn M, Raj A. Goyal Y, et al. Nature. 2023 Aug;620(7974):651-659. doi: 10.1038/s41586-023-06342-8. Epub 2023 Jul 19. Nature. 2023. PMID: 37468627 Free PMC article.
ClampFISH 2.0 enables rapid, scalable amplified RNA detection in situ.
Dardani I, Emert BL, Goyal Y, Jiang CL, Kaur A, Lee J, Rouhanifard SH, Alicea GM, Fane ME, Xiao M, Herlyn M, Weeraratna AT, Raj A. Dardani I, et al. Among authors: goyal y. Nat Methods. 2022 Nov;19(11):1403-1410. doi: 10.1038/s41592-022-01653-6. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280724 Free PMC article.
ERK hyperactivation serves as a unified mechanism of escape in intrinsic and acquired CDK4/6 inhibitor resistance in acral lentiginous melanoma.
Jagirdar K, Portuallo ME, Wei M, Wilhide M, Bravo Narula JA, Robertson BM, Alicea GM, Aguh C, Xiao M, Godok T, Fingerman D, Brown GS, Herlyn M, Elad VM, Guo X, Toska E, Zabransky DJ, Wubbenhorst B, Nathanson KL, Kwatra S, Goyal Y, Ji H, Liu Q, Rebecca VW. Jagirdar K, et al. Among authors: goyal y. Oncogene. 2024 Feb;43(6):395-405. doi: 10.1038/s41388-023-02900-6. Epub 2023 Dec 8. Oncogene. 2024. PMID: 38066089 Free PMC article.
TGF-β blockade drives a transitional effector phenotype in T cells reversing SIV latency and decreasing SIV reservoirs in vivo.
Kim J, Bose D, Araínga M, Haque MR, Fennessey CM, Caddell RA, Thomas Y, Ferrell DE, Ali S, Grody E, Goyal Y, Cicala C, Arthos J, Keele BF, Vaccari M, Lorenzo-Redondo R, Hope TJ, Villinger F, Martinelli E. Kim J, et al. Among authors: goyal y. Nat Commun. 2024 Feb 14;15(1):1348. doi: 10.1038/s41467-024-45555-x. Nat Commun. 2024. PMID: 38355731 Free PMC article.
62 results