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Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R, Wischhusen J. Haake M, et al. Among authors: nimmerjahn f. Nat Commun. 2023 Jul 20;14(1):4253. doi: 10.1038/s41467-023-39817-3. Nat Commun. 2023. PMID: 37474523 Free PMC article.
Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis.
Azizov V, Dietel K, Steffen F, Dürholz K, Meidenbauer J, Lucas S, Frech M, Omata Y, Tajik N, Knipfer L, Kolenbrander A, Seubert S, Lapuente D, Sokolova MV, Hofmann J, Tenbusch M, Ramming A, Steffen U, Nimmerjahn F, Linker R, Wirtz S, Herrmann M, Temchura V, Sarter K, Schett G, Zaiss MM. Azizov V, et al. Among authors: nimmerjahn f. Nat Commun. 2020 Apr 24;11(1):1998. doi: 10.1038/s41467-020-15855-z. Nat Commun. 2020. PMID: 32332730 Free PMC article.
Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.
Harre U, Lang SC, Pfeifle R, Rombouts Y, Frühbeißer S, Amara K, Bang H, Lux A, Koeleman CA, Baum W, Dietel K, Gröhn F, Malmström V, Klareskog L, Krönke G, Kocijan R, Nimmerjahn F, Toes RE, Herrmann M, Scherer HU, Schett G. Harre U, et al. Among authors: nimmerjahn f. Nat Commun. 2015 Mar 31;6:6651. doi: 10.1038/ncomms7651. Nat Commun. 2015. PMID: 25825024 Free PMC article.
Immunoglobulin G-dependent inhibition of inflammatory bone remodeling requires pattern recognition receptor Dectin-1.
Seeling M, Pöhnl M, Kara S, Horstmann N, Riemer C, Wöhner M, Liang C, Brückner C, Eiring P, Werner A, Biburger M, Altmann L, Schneider M, Amon L, Lehmann CHK, Lee S, Kunz M, Dudziak D, Schett G, Bäuerle T, Lux A, Tuckermann J, Vögtle T, Nieswandt B, Sauer M, Böckmann RA, Nimmerjahn F. Seeling M, et al. Among authors: nimmerjahn f. Immunity. 2023 May 9;56(5):1046-1063.e7. doi: 10.1016/j.immuni.2023.02.019. Epub 2023 Mar 21. Immunity. 2023. PMID: 36948194 Free article.
B-cell inhibition by cross-linking CD79b is superior to B-cell depletion with anti-CD20 antibodies in treating murine collagen-induced arthritis.
Brühl H, Cihak J, Talke Y, Rodriguez Gomez M, Hermann F, Goebel N, Renner K, Plachý J, Stangassinger M, Aschermann S, Nimmerjahn F, Mack M. Brühl H, et al. Among authors: nimmerjahn f. Eur J Immunol. 2015 Mar;45(3):705-15. doi: 10.1002/eji.201444971. Epub 2014 Dec 28. Eur J Immunol. 2015. PMID: 25471597 Free article.
221 results