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Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R, Wischhusen J. Haake M, et al. Among authors: rooswinkel rw. Nat Commun. 2023 Jul 20;14(1):4253. doi: 10.1038/s41467-023-39817-3. Nat Commun. 2023. PMID: 37474523 Free PMC article.
Acquiring orphans.
Rooswinkel R, Mulder GJ, van Deventer S. Rooswinkel R, et al. Nat Biotechnol. 2014 Mar;32(3):213-6. doi: 10.1038/nbt.2836. Nat Biotechnol. 2014. PMID: 24727767 No abstract available.
Venturing across the Atlantic.
Rooswinkel RW, Berbers DS, Claassen EH, van Deventer S. Rooswinkel RW, et al. Nat Biotechnol. 2016 Nov 8;34(11):1095-1098. doi: 10.1038/nbt.3712. Nat Biotechnol. 2016. PMID: 27824845 No abstract available.
Mapping the European startup landscape.
van Wilgenburg B, van Wilgenburg K, Paisner K, van Deventer S, Rooswinkel RW. van Wilgenburg B, et al. Among authors: rooswinkel rw. Nat Biotechnol. 2019 Apr;37(4):345-349. doi: 10.1038/s41587-019-0076-4. Nat Biotechnol. 2019. PMID: 30940934 No abstract available.
Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.
van Waterschoot RA, ter Heine R, Wagenaar E, van der Kruijssen CM, Rooswinkel RW, Huitema AD, Beijnen JH, Schinkel AH. van Waterschoot RA, et al. Among authors: rooswinkel rw. Br J Pharmacol. 2010 Jul;160(5):1224-33. doi: 10.1111/j.1476-5381.2010.00759.x. Br J Pharmacol. 2010. PMID: 20590614 Free PMC article.
15 results