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A conserved isoleucine in the binding pocket of RIG-I controls immune tolerance to mitochondrial RNA.
Nucleic Acids Res. 2023 Nov 27;51(21):11893-11910. doi: 10.1093/nar/gkad835.
Nucleic Acids Res. 2023.
PMID: 37831086
Free PMC article.
Tumor-derived GDF-15 blocks LFA-1 dependent T cell recruitment and suppresses responses to anti-PD-1 treatment.
Haake M, Haack B, Schäfer T, Harter PN, Mattavelli G, Eiring P, Vashist N, Wedekink F, Genssler S, Fischer B, Dahlhoff J, Mokhtari F, Kuzkina A, Welters MJP, Benz TM, Sorger L, Thiemann V, Almanzar G, Selle M, Thein K, Späth J, Gonzalez MC, Reitinger C, Ipsen-Escobedo A, Wistuba-Hamprecht K, Eichler K, Filipski K, Zeiner PS, Beschorner R, Goedemans R, Gogolla FH, Hackl H, Rooswinkel RW, Thiem A, Roche PR, Joshi H, Pühringer D, Wöckel A, Diessner JE, Rüdiger M, Leo E, Cheng PF, Levesque MP, Goebeler M, Sauer M, Nimmerjahn F, Schuberth-Wagner C, von Felten S, Mittelbronn M, Mehling M, Beilhack A, van der Burg SH, Riedel A, Weide B, Dummer R, Wischhusen J.
Haake M, et al. Among authors: schuberth wagner c.
Nat Commun. 2023 Jul 20;14(1):4253. doi: 10.1038/s41467-023-39817-3.
Nat Commun. 2023.
PMID: 37474523
Free PMC article.
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RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.
Coch C, Stümpel JP, Lilien-Waldau V, Wohlleber D, Kümmerer BM, Bekeredjian-Ding I, Kochs G, Garbi N, Herberhold S, Schuberth-Wagner C, Ludwig J, Barchet W, Schlee M, Hoerauf A, Bootz F, Staeheli P, Hartmann G, Hartmann E.
Coch C, et al. Among authors: schuberth wagner c.
Mol Ther. 2017 Sep 6;25(9):2093-2103. doi: 10.1016/j.ymthe.2017.07.003. Epub 2017 Jul 8.
Mol Ther. 2017.
PMID: 28760668
Free PMC article.
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RIG-I activation induces the release of extracellular vesicles with antitumor activity.
Daßler-Plenker J, Reiners KS, van den Boorn JG, Hansen HP, Putschli B, Barnert S, Schuberth-Wagner C, Schubert R, Tüting T, Hallek M, Schlee M, Hartmann G, Pogge von Strandmann E, Coch C.
Daßler-Plenker J, et al. Among authors: schuberth wagner c.
Oncoimmunology. 2016 Aug 19;5(10):e1219827. doi: 10.1080/2162402X.2016.1219827. eCollection 2016.
Oncoimmunology. 2016.
PMID: 27853642
Free PMC article.
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A Conserved Histidine in the RNA Sensor RIG-I Controls Immune Tolerance to N1-2'O-Methylated Self RNA.
Schuberth-Wagner C, Ludwig J, Bruder AK, Herzner AM, Zillinger T, Goldeck M, Schmidt T, Schmid-Burgk JL, Kerber R, Wolter S, Stümpel JP, Roth A, Bartok E, Drosten C, Coch C, Hornung V, Barchet W, Kümmerer BM, Hartmann G, Schlee M.
Schuberth-Wagner C, et al.
Immunity. 2015 Jul 21;43(1):41-51. doi: 10.1016/j.immuni.2015.06.015. Epub 2015 Jul 14.
Immunity. 2015.
PMID: 26187414
Free PMC article.
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