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Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia.
Lips ES, Cornelisse LN, Toonen RF, Min JL, Hultman CM; International Schizophrenia Consortium; Holmans PA, O'Donovan MC, Purcell SM, Smit AB, Verhage M, Sullivan PF, Visscher PM, Posthuma D. Lips ES, et al. Among authors: posthuma d. Mol Psychiatry. 2012 Oct;17(10):996-1006. doi: 10.1038/mp.2011.117. Epub 2011 Sep 20. Mol Psychiatry. 2012. PMID: 21931320 Free PMC article.
Childhood intelligence is heritable, highly polygenic and associated with FNBP1L.
Benyamin B, Pourcain B, Davis OS, Davies G, Hansell NK, Brion MJ, Kirkpatrick RM, Cents RA, Franić S, Miller MB, Haworth CM, Meaburn E, Price TS, Evans DM, Timpson N, Kemp J, Ring S, McArdle W, Medland SE, Yang J, Harris SE, Liewald DC, Scheet P, Xiao X, Hudziak JJ, de Geus EJ; Wellcome Trust Case Control Consortium 2 (WTCCC2); Jaddoe VW, Starr JM, Verhulst FC, Pennell C, Tiemeier H, Iacono WG, Palmer LJ, Montgomery GW, Martin NG, Boomsma DI, Posthuma D, McGue M, Wright MJ, Davey Smith G, Deary IJ, Plomin R, Visscher PM. Benyamin B, et al. Among authors: posthuma d. Mol Psychiatry. 2014 Feb;19(2):253-8. doi: 10.1038/mp.2012.184. Epub 2013 Jan 29. Mol Psychiatry. 2014. PMID: 23358156 Free PMC article.
Gene expression in major depressive disorder.
Jansen R, Penninx BW, Madar V, Xia K, Milaneschi Y, Hottenga JJ, Hammerschlag AR, Beekman A, van der Wee N, Smit JH, Brooks AI, Tischfield J, Posthuma D, Schoevers R, van Grootheest G, Willemsen G, de Geus EJ, Boomsma DI, Wright FA, Zou F, Sun W, Sullivan PF. Jansen R, et al. Among authors: posthuma d. Mol Psychiatry. 2016 Mar;21(3):339-47. doi: 10.1038/mp.2015.57. Epub 2015 May 26. Mol Psychiatry. 2016. PMID: 26008736
Modeling psychiatric disorders: from genomic findings to cellular phenotypes.
Falk A, Heine VM, Harwood AJ, Sullivan PF, Peitz M, Brüstle O, Shen S, Sun YM, Glover JC, Posthuma D, Djurovic S. Falk A, et al. Among authors: posthuma d. Mol Psychiatry. 2016 Sep;21(9):1167-79. doi: 10.1038/mp.2016.89. Epub 2016 May 31. Mol Psychiatry. 2016. PMID: 27240529 Free PMC article. Review.
Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.
Tielbeek JJ, Johansson A, Polderman TJC, Rautiainen MR, Jansen P, Taylor M, Tong X, Lu Q, Burt AS, Tiemeier H, Viding E, Plomin R, Martin NG, Heath AC, Madden PAF, Montgomery G, Beaver KM, Waldman I, Gelernter J, Kranzler HR, Farrer LA, Perry JRB, Munafò M, LoParo D, Paunio T, Tiihonen J, Mous SE, Pappa I, de Leeuw C, Watanabe K, Hammerschlag AR, Salvatore JE, Aliev F, Bigdeli TB, Dick D, Faraone SV, Popma A, Medland SE, Posthuma D; Broad Antisocial Behavior Consortium collaborators. Tielbeek JJ, et al. Among authors: posthuma d. JAMA Psychiatry. 2017 Dec 1;74(12):1242-1250. doi: 10.1001/jamapsychiatry.2017.3069. JAMA Psychiatry. 2017. PMID: 28979981 Free PMC article.
Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations.
Milaneschi Y, Lamers F, Peyrot WJ, Baune BT, Breen G, Dehghan A, Forstner AJ, Grabe HJ, Homuth G, Kan C, Lewis C, Mullins N, Nauck M, Pistis G, Preisig M, Rivera M, Rietschel M, Streit F, Strohmaier J, Teumer A, Van der Auwera S, Wray NR, Boomsma DI, Penninx BWJH; CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Milaneschi Y, et al. JAMA Psychiatry. 2017 Dec 1;74(12):1214-1225. doi: 10.1001/jamapsychiatry.2017.3016. JAMA Psychiatry. 2017. PMID: 29049554 Free PMC article.
An epigenome-wide association study meta-analysis of educational attainment.
Karlsson Linnér R, Marioni RE, Rietveld CA, Simpkin AJ, Davies NM, Watanabe K, Armstrong NJ, Auro K, Baumbach C, Bonder MJ, Buchwald J, Fiorito G, Ismail K, Iurato S, Joensuu A, Karell P, Kasela S, Lahti J, McRae AF, Mandaviya PR, Seppälä I, Wang Y, Baglietto L, Binder EB, Harris SE, Hodge AM, Horvath S, Hurme M, Johannesson M, Latvala A, Mather KA, Medland SE, Metspalu A, Milani L, Milne RL, Pattie A, Pedersen NL, Peters A, Polidoro S, Räikkönen K, Severi G, Starr JM, Stolk L, Waldenberger M, Eriksson JG, Esko T, Franke L, Gieger C, Giles GG, Hägg S, Jousilahti P, Kaprio J, Kähönen M, Lehtimäki T, Martin NG, van Meurs JBC, Ollikainen M, Perola M, Posthuma D, Raitakari OT, Sachdev PS, Taskesen E, Uitterlinden AG, Vineis P, Wijmenga C, Wright MJ, Relton C, Davey Smith G, Deary IJ, Koellinger PD, Benjamin DJ. Karlsson Linnér R, et al. Among authors: posthuma d. Mol Psychiatry. 2017 Dec;22(12):1680-1690. doi: 10.1038/mp.2017.210. Epub 2017 Oct 31. Mol Psychiatry. 2017. PMID: 29086770 Free PMC article.
Biological annotation of genetic loci associated with intelligence in a meta-analysis of 87,740 individuals.
Coleman JRI, Bryois J, Gaspar HA, Jansen PR, Savage JE, Skene N, Plomin R, Muñoz-Manchado AB, Linnarsson S, Crawford G, Hjerling-Leffler J, Sullivan PF, Posthuma D, Breen G. Coleman JRI, et al. Among authors: posthuma d. Mol Psychiatry. 2019 Feb;24(2):182-197. doi: 10.1038/s41380-018-0040-6. Epub 2018 Mar 8. Mol Psychiatry. 2019. PMID: 29520040 Free PMC article.
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.
Savage JE, Jansen PR, Stringer S, Watanabe K, Bryois J, de Leeuw CA, Nagel M, Awasthi S, Barr PB, Coleman JRI, Grasby KL, Hammerschlag AR, Kaminski JA, Karlsson R, Krapohl E, Lam M, Nygaard M, Reynolds CA, Trampush JW, Young H, Zabaneh D, Hägg S, Hansell NK, Karlsson IK, Linnarsson S, Montgomery GW, Muñoz-Manchado AB, Quinlan EB, Schumann G, Skene NG, Webb BT, White T, Arking DE, Avramopoulos D, Bilder RM, Bitsios P, Burdick KE, Cannon TD, Chiba-Falek O, Christoforou A, Cirulli ET, Congdon E, Corvin A, Davies G, Deary IJ, DeRosse P, Dickinson D, Djurovic S, Donohoe G, Conley ED, Eriksson JG, Espeseth T, Freimer NA, Giakoumaki S, Giegling I, Gill M, Glahn DC, Hariri AR, Hatzimanolis A, Keller MC, Knowles E, Koltai D, Konte B, Lahti J, Le Hellard S, Lencz T, Liewald DC, London E, Lundervold AJ, Malhotra AK, Melle I, Morris D, Need AC, Ollier W, Palotie A, Payton A, Pendleton N, Poldrack RA, Räikkönen K, Reinvang I, Roussos P, Rujescu D, Sabb FW, Scult MA, Smeland OB, Smyrnis N, Starr JM, Steen VM, Stefanis NC, Straub RE, Sundet K, Tiemeier H, Voineskos AN, Weinberger DR, Widen E, Yu J, Abecasis G, Andreassen OA, Breen G, Christiansen L, Debrabant B, Dick DM, Heinz A, Hjerling-Leffle… See abstract for full author list ➔ Savage JE, et al. Among authors: posthuma d. Nat Genet. 2018 Jul;50(7):912-919. doi: 10.1038/s41588-018-0152-6. Epub 2018 Jun 25. Nat Genet. 2018. PMID: 29942086 Free PMC article.
374 results