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418 results

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Page 1
Pig-to-human heart xenotransplantation in two recently deceased human recipients.
Moazami N, Stern JM, Khalil K, Kim JI, Narula N, Mangiola M, Weldon EP, Kagermazova L, James L, Lawson N, Piper GL, Sommer PM, Reyentovich A, Bamira D, Saraon T, Kadosh BS, DiVita M, Goldberg RI, Hussain ST, Chan J, Ngai J, Jan T, Ali NM, Tatapudi VS, Segev DL, Bisen S, Jaffe IS, Piegari B, Kowalski H, Kokkinaki M, Monahan J, Sorrells L, Burdorf L, Boeke JD, Pass H, Goparaju C, Keating B, Ayares D, Lorber M, Griesemer A, Mehta SA, Smith DE, Montgomery RA. Moazami N, et al. Among authors: boeke jd. Nat Med. 2023 Aug;29(8):1989-1997. doi: 10.1038/s41591-023-02471-9. Epub 2023 Jul 24. Nat Med. 2023. PMID: 37488288
Results of Two Cases of Pig-to-Human Kidney Xenotransplantation.
Montgomery RA, Stern JM, Lonze BE, Tatapudi VS, Mangiola M, Wu M, Weldon E, Lawson N, Deterville C, Dieter RA, Sullivan B, Boulton G, Parent B, Piper G, Sommer P, Cawthon S, Duggan E, Ayares D, Dandro A, Fazio-Kroll A, Kokkinaki M, Burdorf L, Lorber M, Boeke JD, Pass H, Keating B, Griesemer A, Ali NM, Mehta SA, Stewart ZA. Montgomery RA, et al. Among authors: boeke jd. N Engl J Med. 2022 May 19;386(20):1889-1898. doi: 10.1056/NEJMoa2120238. N Engl J Med. 2022. PMID: 35584156
Integrative multi-omics profiling in human decedents receiving pig heart xenografts.
Schmauch E, Piening B, Mohebnasab M, Xia B, Zhu C, Stern J, Zhang W, Dowdell AK, Kim JI, Andrijevic D, Khalil K, Jaffe IS, Loza BL, Gragert L, Camellato BR, Oliveira MF, O'Brien DP, Chen HM, Weldon E, Gao H, Gandla D, Chang A, Bhatt R, Gao S, Lin X, Reddy KP, Kagermazova L, Habara AH, Widawsky S, Liang FX, Sall J, Loupy A, Heguy A, Taylor SEB, Zhu Y, Michael B, Jiang L, Jian R, Chong AS, Fairchild RL, Linna-Kuosmanen S, Kaikkonen MU, Tatapudi V, Lorber M, Ayares D, Mangiola M, Narula N, Moazami N, Pass H, Herati RS, Griesemer A, Kellis M, Snyder MP, Montgomery RA, Boeke JD, Keating BJ. Schmauch E, et al. Among authors: boeke jd. Nat Med. 2024 May;30(5):1448-1460. doi: 10.1038/s41591-024-02972-1. Epub 2024 May 17. Nat Med. 2024. PMID: 38760586
L1 drives IFN in senescent cells and promotes age-associated inflammation.
De Cecco M, Ito T, Petrashen AP, Elias AE, Skvir NJ, Criscione SW, Caligiana A, Brocculi G, Adney EM, Boeke JD, Le O, Beauséjour C, Ambati J, Ambati K, Simon M, Seluanov A, Gorbunova V, Slagboom PE, Helfand SL, Neretti N, Sedivy JM. De Cecco M, et al. Among authors: boeke jd. Nature. 2019 Feb;566(7742):73-78. doi: 10.1038/s41586-018-0784-9. Epub 2019 Feb 6. Nature. 2019. PMID: 30728521 Free PMC article.
The role of retrotransposable elements in ageing and age-associated diseases.
Gorbunova V, Seluanov A, Mita P, McKerrow W, Fenyö D, Boeke JD, Linker SB, Gage FH, Kreiling JA, Petrashen AP, Woodham TA, Taylor JR, Helfand SL, Sedivy JM. Gorbunova V, et al. Among authors: boeke jd. Nature. 2021 Aug;596(7870):43-53. doi: 10.1038/s41586-021-03542-y. Epub 2021 Aug 4. Nature. 2021. PMID: 34349292 Free PMC article. Review.
Mouse genome rewriting and tailoring of three important disease loci.
Zhang W, Golynker I, Brosh R, Fajardo A, Zhu Y, Wudzinska AM, Ordoñez R, Ribeiro-Dos-Santos AM, Carrau L, Damani-Yokota P, Yeung ST, Khairallah C, Vela Gartner A, Chalhoub N, Huang E, Ashe HJ, Khanna KM, Maurano MT, Kim SY, tenOever BR, Boeke JD. Zhang W, et al. Among authors: boeke jd. Nature. 2023 Nov;623(7986):423-431. doi: 10.1038/s41586-023-06675-4. Epub 2023 Nov 1. Nature. 2023. PMID: 37914927 Free PMC article.
On the genetic basis of tail-loss evolution in humans and apes.
Xia B, Zhang W, Zhao G, Zhang X, Bai J, Brosh R, Wudzinska A, Huang E, Ashe H, Ellis G, Pour M, Zhao Y, Coelho C, Zhu Y, Miller A, Dasen JS, Maurano MT, Kim SY, Boeke JD, Yanai I. Xia B, et al. Among authors: boeke jd. Nature. 2024 Feb;626(8001):1042-1048. doi: 10.1038/s41586-024-07095-8. Epub 2024 Feb 28. Nature. 2024. PMID: 38418917 Free PMC article.
Synthetic reversed sequences reveal default genomic states.
Camellato BR, Brosh R, Ashe HJ, Maurano MT, Boeke JD. Camellato BR, et al. Among authors: boeke jd. Nature. 2024 Apr;628(8007):373-380. doi: 10.1038/s41586-024-07128-2. Epub 2024 Mar 6. Nature. 2024. PMID: 38448583 Free PMC article.
418 results